公开(公告)号：US11899024B2

公开(公告)日：2024-02-13

申请号：US16629000

申请日：2018-07-12

Applicant: Exosome Diagnostics, Inc.

Inventor： Mia Sher ,  Erez Eitan ,  Christine Coticchia ,  Johan Karl Olov Skog ,  Robert Kitchen ,  Seth Yu

IPC: G01N33/68 ,  G01N33/537 ,  C12N15/10

CPC classification number: G01N33/6896 ,  C12N15/1013 ,  G01N33/537 ,  G01N2333/705 ,  G01N2800/28

Abstract: The invention relates generally to a process for isolating subpopulations of EVs to identify biomarkers useful identifying, determining the progression of, and/or prognosing a disease, including a neurological disease. More particularly, the present invention relates to detection technology of various exosomal biomarkers including proteins, protein modifications, sugars, RNA, DNA, lipids, and metabolites, and combinations thereof.