公开(公告)号：US20240309426A1

公开(公告)日：2024-09-19

申请号：US18589016

申请日：2024-02-27

Applicant: Exact Sciences Cororation

Inventor： Hatim T. Allawi ,  Graham P. Lidgard ,  Brian Aizenstein ,  Melissa M. Gray

IPC: C12Q1/6806 ,  C12N15/10

CPC classification number: C12Q1/6806 ,  C12N15/1006 ,  C12Q2600/154 ,  C12Q2600/16

Abstract: The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods. In particular, provided herein are synthetic methylated DNA strands of known composition for use as control molecules in DNA testing, e.g., of mutations and/or methylation of DNA isolated from non-fish samples, such as human samples.