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公开(公告)号:US08614090B2
公开(公告)日:2013-12-24
申请号:US12859068
申请日:2010-08-18
申请人: Eric Delwart , Amit Kapoor , Li Linlin
发明人: Eric Delwart , Amit Kapoor , Li Linlin
CPC分类号: C12Q1/70 , C07K14/005 , C12N7/00 , C12N2770/12022 , C12N2770/12051
摘要: Provided herein are sequences of the genomes and encoded proteins of new astrovirus species, and variants thereof. Also provided are methods of detecting the new astrovirus species and diagnosing astrovirus infection, methods of treating or preventing astrovirus infection, and methods for identifying anti-astrovirus compounds.Provided are two new astrovirus species named HMOAstV-A and HMOAstV-B, and both are distantly related to known astroviruses. Also provided is a new method of classifying astroviruses, where there are three groups of human astroviruses, including HAstV, AstV-MLB, and HMOAstV.
摘要翻译: 本文提供了新型星状病毒物种的基因组和编码蛋白质的序列及其变体。 还提供了检测新的星状病毒物种和诊断星状病毒感染的方法,治疗或预防星状病毒感染的方法以及用于鉴定抗星状病毒化合物的方法。 提供两种名为HMOAstV-A和HMOAstV-B的新型星状病毒物种,两者都与已知的星状病毒密切相关。 还提供了一种分类星状病毒的新方法,其中有三组人类星状病毒,包括HAstV,AstV-MLB和HMOAstV。
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公开(公告)号:US20120100168A1
公开(公告)日:2012-04-26
申请号:US13012777
申请日:2011-01-24
申请人: Eric Delwart , Li Linlin
发明人: Eric Delwart , Li Linlin
IPC分类号: A61K39/12 , C07K14/01 , C07K16/08 , C12N7/00 , C12N15/63 , A61P31/20 , G01N33/50 , C12Q1/68 , C12Q1/70 , C07H21/02 , A61P31/12 , C07H21/04 , C12N1/21
CPC分类号: C12Q1/70 , Y10T436/143333
摘要: Provided herein are sequences of the genomes and encoded proteins of a novel virus, termed cyclovirus, and variants thereof. Also provided are methods of detecting cyclovirus and diagnosing cyclovirus infection, methods of treating or preventing cyclovirus infection, and methods for identifying anti-cyclovirus compounds. Further provided are vaccines and methods of preventing cyclovirus-related diseases in animals, such as pigs.
摘要翻译: 本文提供了称为环病毒的新型病毒的基因组和编码的蛋白质的序列及其变体。 还提供了检测环状病毒和诊断环状病毒感染的方法,治疗或预防环状病毒感染的方法,以及鉴定抗环状病毒化合物的方法。 进一步提供疫苗和预防动物如猪的环状病毒相关疾病的方法。
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