公开(公告)号：US20230020092A1

公开(公告)日：2023-01-19

申请号：US17757421

申请日：2020-12-21

申请人： Entrada Therapeutics, Inc.

发明人： Ziqing Qian ,  Xiang Li ,  Mahboubeh Kheirabadi ,  Mohanraj Dhanabal ,  Haoming Liu ,  Xiulong Shen ,  Kimberli Kamer ,  Natarajan Sethuraman

IPC分类号： C07K7/64 ,  C12N15/113

摘要： Provided herein are compounds comprising cyclic cell penetrating peptides and antisense compounds. Also provided herein are methods of modulating splicing, inhibiting or regulating translation, mediating degradation, blocking expansions of nucleotide repeats, and treating disease using the aforementioned compounds.