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公开(公告)号：US20240327535A1
公开(公告)日：2024-10-03
申请号：US18741705
申请日：2024-06-12
发明人： Ryan Henry , Thiwanka Samarakoon , Nathan Fishkin , Ping Zhu , Ermira Pazolli , James Palacino , Juan C. Almagro
IPC分类号： C07K16/28 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/60 , A61K47/65 , A61K47/68 , A61P35/00
CPC分类号： C07K16/2878 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K47/65 , A61K47/6803 , A61K47/6849 , A61P35/00 , A61K2039/505 , C07K2317/92
摘要： Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
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公开(公告)号：US12043670B2
公开(公告)日：2024-07-23
申请号：US17339549
申请日：2021-06-04
发明人： Ryan Henry , Thiwanka Samarakoon , Nathan Fishkin , Ping Zhu , Ermira Pazolli , James Palacino , Juan C. Almagro
IPC分类号： C07K16/28 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/60 , A61K47/65 , A61K47/68 , A61P35/00
CPC分类号： C07K16/2878 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K47/65 , A61K47/6803 , A61K47/6849 , A61P35/00 , A61K2039/505 , C07K2317/92
摘要： Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
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公开(公告)号：US20220081486A1
公开(公告)日：2022-03-17
申请号：US17339549
申请日：2021-06-04
发明人： Ryan Henry , Thiwanka Samarakoon , Nathan Fishkin , Ping Zhu , Ermira Pazolli , James Palacino , Juan C. Almagro
摘要： Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
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