- 专利标题： ANTI-BCMA ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
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申请号： US18741705申请日： 2024-06-12
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公开(公告)号： US20240327535A1公开(公告)日： 2024-10-03
- 发明人: Ryan Henry , Thiwanka Samarakoon , Nathan Fishkin , Ping Zhu , Ermira Pazolli , James Palacino , Juan C. Almagro
- 申请人： Eisai R&D Management Co., Ltd.
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 分案原申请号： US17339549 2021.06.04
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/00 ; A61K39/395 ; A61K45/06 ; A61K47/60 ; A61K47/65 ; A61K47/68 ; A61P35/00
摘要：
Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
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