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    Methods of loading a prosthetic valve in a delivery apparatus
    2.
    发明授权
    Methods of loading a prosthetic valve in a delivery apparatus 有权

    公开(公告)号：US10952848B2

    公开(公告)日：2021-03-23

    申请号：US15953991

    申请日：2018-04-16

    Applicant: Edwards Lifesciences Corporation

    Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

    IPC: A61F2/24 ,  A61F2/95

    Abstract: Embodiments of the present disclosure provide methods of loading a prosthetic heart valve within a delivery apparatus such that it can be used for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The methods can include attaching the prosthetic heart valve to a valve-retaining mechanism at a distal end of the catheter and causing a torque shaft of the delivery apparatus to rotate relative to the catheter, wherein the torque shaft extends within the catheter and is coupled to the valve delivery sheath. Rotation of the torque shaft relative to the catheter can cause relative longitudinal movement between the valve sheath and the prosthetic heart valve such that the prosthetic heart valve is covered by the valve sheath.

    PERIVALVULAR SEALING FOR TRANSCATHETER HEART VALVE
    4.
    发明申请
    PERIVALVULAR SEALING FOR TRANSCATHETER HEART VALVE 审中-公开

    公开(公告)号：US20190380833A1

    公开(公告)日：2019-12-19

    申请号：US16554014

    申请日：2019-08-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Ziv Yohanan ,  Nikolay Gurovich ,  Bella Felsen ,  Itai Pelled ,  Oded Meiri

    IPC: A61F2/24

    Abstract: A prosthetic heart valve includes a frame, a valvular structure coupled to the frame, and a sealing member coupled to the frame. The frame has inflow and outflow ends and a lumen extending therebetween. The frame includes struts that form cells, and the cells are arranged in three rows. The frame is radially expandable from a collapsed state to an expanded state. The valvular structure includes a plurality of leaflets configured to allow blood flow through the lumen of the frame from the inflow end to the outflow end and to block blood flow through the lumen of the frame from the outflow end to the inflow end. The sealing skirt extends from an intermediate location of the frame disposed between the inflow and outflow ends to the inflow end of the frame. The sealing skirt covers two rows of cells to block blood flow through the cells.

    PERIVALVULAR SEALING FOR TRANSCATHETER HEART VALVE
    5.
    发明申请
    PERIVALVULAR SEALING FOR TRANSCATHETER HEART VALVE 审中-公开

    公开(公告)号：US20180318074A1

    公开(公告)日：2018-11-08

    申请号：US16039215

    申请日：2018-07-18

    Applicant: Edwards Lifesciences Corporation

    Inventor： Ziv Yohanan ,  Nikolay Gurovich ,  Bella Felsen ,  Itai Pelled ,  Oded Meiri

    IPC: A61F2/24

    Abstract: A prosthetic heart valve includes a frame, a valve member, and a sealing member. The frame is expandable from a collapsed state to an expanded state. The frame has inflow and outflow ends, a lumen extending between the ends, and a plurality of struts defining a plurality of cells. The valve member is disposed within the lumen of the frame and is movable between open and closed configurations. The sealing member is mounted inside of the frame. When the frame is in the expanded state and the valve member is in the closed configuration, portions of the sealing member can protrude outwardly through the cells of the frame and extend beyond an exterior surface of the struts of the frame.

    Perivalvular sealing for transcatheter heart valve
    6.
    发明授权
    Perivalvular sealing for transcatheter heart valve 有权

    公开(公告)号：US10076411B2

    公开(公告)日：2018-09-18

    申请号：US15246234

    申请日：2016-08-24

    Applicant: Edwards Lifesciences Corporation

    Inventor： Ziv Yohanan ,  Nikolay Gurovich ,  Bella Felsen ,  Itai Pelled ,  Oded Meiri

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/0065 ,  A61F2250/0069

    Abstract: The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.

    Prosthetic heart valve and delivery apparatus
    9.
    发明授权
    Prosthetic heart valve and delivery apparatus 有权

    公开(公告)号：US11540918B2

    公开(公告)日：2023-01-03

    申请号：US17456355

    申请日：2021-11-23

    Applicant: Edwards Lifesciences Corporation

    Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

    IPC: A61F2/24 ,  A61F2/95

    Abstract: Prosthetic heart valves and methods of implantation thereof are disclosed herein. In embodiments, a prosthetic heart valve includes a self-expandable frame configured to support of valve member and comprising a plurality of interconnected strut members forming a mesh structure. An inflow end and outflow end portions of the mesh structure respectively define an inflow terminal end and an outflow terminal end of the frame. A portion of the frame tapers inwardly from the inflow terminal end to form a reduced diameter section. In implementations, the frame increases in diameter from the reduced diameter section to an intermediate section. In implementations, the valve member is secured to the frame at the inflow end portion. In implementations, the frame further comprises a plurality of retaining arms that extend from the outflow terminal end and are configured to engage with a valve retaining mechanism of a delivery apparatus.

    PROSTHETIC HEART VALVE AND DELIVERY APPARATUS
    10.
    发明申请
    PROSTHETIC HEART VALVE AND DELIVERY APPARATUS 有权

    公开(公告)号：US20210401574A1

    公开(公告)日：2021-12-30

    申请号：US17468414

    申请日：2021-09-07

    Applicant: Edwards Lifesciences Corporation

    Inventor： David Alon ,  Netanel Benichou ,  Oded Meiri

    IPC: A61F2/24

    Abstract: A delivery assembly includes a prosthetic device, a catheter shaft, a release wire, a first line, and a second line. The prosthetic device has a first arm and a second arm. The release wire extends through the catheter shaft. The first line includes a first loop. The first line extends from the catheter shaft, through the first arm of the prosthetic device, and to the release wire, where the release wire extends through the first loop. The second line includes a second loop. The second line extends from the catheter shaft, through the second arm of the prosthetic device, and to the release wire, where the release wire extends through the second loop.

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