公开(公告)号：US20230414825A1

公开(公告)日：2023-12-28

申请号：US18464230

申请日：2023-09-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Ekaterina Tkatchouk ,  Maria L. Saravia

IPC: A61L17/14 ,  A61L17/10

CPC classification number: A61L17/145 ,  A61L17/10 ,  A61L2420/02

Abstract: A method of preparing a suture for use in medical treatment involves treating a surface of the suture, applying a coating to the suture, and treating the coating to cause adhesion of the coating to the suture.

公开(公告)号：US20230310155A1

公开(公告)日：2023-10-05

申请号：US18328608

申请日：2023-06-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Stephen Cournane ,  Wesley Paul Nicholson ,  Harvey H. Chen ,  Maria L. Saravia ,  Derrick Johnson ,  Felino V. Cortez, JR. ,  Stephen Epstein ,  Luke Anthony Zanetti

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61F2/2457 ,  A61F2220/0075 ,  A61F2220/0016 ,  A61B2017/0409

Abstract: A delivery system comprises two or more needles including at least a first needle comprising a distal tip configured to pierce a valve leaflet of a heart, two or more leaflet anchors, each of the two or more leaflet anchors configured to be delivered via one of the two or more needles, and a shaft comprising a first interior lumen configured to slidably receive the two or more needles, the shaft having a first opening into the first interior lumen at a distal end of the shaft, the first opening configured to allow at least the first needle to exit the shaft.

公开(公告)号：US20230233326A1

公开(公告)日：2023-07-27

申请号：US18190025

申请日：2023-03-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Brian S. Conklin ,  Maria L. Saravia ,  Harvey H. Chen ,  Cindy Woo

IPC: A61F2/24 ,  A61B17/04

CPC classification number: A61F2/2466 ,  A61F2/2457 ,  A61B17/0401 ,  A61F2220/0075 ,  A61F2220/0008 ,  A61B2017/0406 ,  A61B2017/0409 ,  A61B2017/0464 ,  A61B2017/00243

Abstract: A method comprises inserting a needle into a ventricle of a heart. The needle is configured to deliver a first anchoring element, a second anchoring element, and a tethering suture to the ventricle. The tethering suture is tethered between the first anchoring element and the second anchoring element. The method further comprises penetrating a first leaflet of a heart valve with the needle, penetrating a second leaflet of the heart valve with the needle, deploying the first anchoring element at a distal side of the second leaflet, retracting the needle from the first leaflet and the second leaflet, deploying the second anchoring element at a proximal side of the first leaflet, cinching the tethering suture to cause a desired amount of valve coaptation, and locking the tethering suture.

公开(公告)号：US11998448B2

公开(公告)日：2024-06-04

申请号：US17479225

申请日：2021-09-20

Applicant: Edwards Lifesciences Corporation

Inventor： Brian C. Gray ,  Tung T. Le ,  Andrew Oien ,  Sonny Tran ,  Thanh Huy Le ,  Robert Bowes ,  Maria L. Saravia ,  Uy D. Trinh ,  Hamid Rafi ,  Alejandro J. Froimovich Rosenberg

IPC: A61F2/24 ,  A61F2/95

CPC classification number: A61F2/2436 ,  A61F2/9517

Abstract: Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

公开(公告)号：US11123188B2

公开(公告)日：2021-09-21

申请号：US16208457

申请日：2018-12-03

Applicant: Edwards Lifesciences Corporation

Inventor： Brian C. Gray ,  Tung T. Le ,  Andrew Oien ,  Sonny Tran ,  Thanh Huy Le ,  Robert Bowes ,  Maria L. Saravia ,  Uy D. Trinh ,  Hamid Rafi ,  Alejandro J. Froimovich Rosenberg

IPC: A61F2/24 ,  A61F2/95

Abstract: Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

公开(公告)号：US20200069426A1

公开(公告)日：2020-03-05

申请号：US16549957

申请日：2019-08-23

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Maria L. Saravia ,  Adam J. Yestrepsky ,  Derrick Johnson ,  Rodolfo Rodriguez ,  Sai Prasad Uppalapati ,  Louis A. Campbell

IPC: A61F2/24

Abstract: Systems, apparatuses, and methods disclosed herein are provided for medical treatment, including transcatheter medical treatments and/or for treatment of dilated hearts (e.g., dilated left ventricle) or functional mitral valve regurgitation within a human heart. The systems, apparatuses, and methods disclosed herein may include applying one or more heart splints to the patient's heart to apply pressure to the heart to reshape the heart. Anchors disclosed herein may be utilized in plugs for treating openings in a septum between two chambers of a heart, e.g., ventricular septal defects (VSD), atrial septal defects (ASD), and patent foramen ovale (PFO). In addition, the anchors disclosed herein may be utilized to reshape an annulus of a patient's heart valve, including a tricuspid valve of a patient's heart. The anchors disclosed herein may also be utilized to reposition a heart valve leaflet to reduce heart valve leaflet prolapse.

公开(公告)号：US20240173034A1

公开(公告)日：2024-05-30

申请号：US18431809

申请日：2024-02-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Harvey H. Chen ,  Manouchehr A. Miraki ,  Rodolfo Rodriguez ,  Erin E. Castioni ,  Maria L. Saravia ,  Stephen Epstein ,  Luke Anthony Zanetti ,  Ashley Nicolette Hinga (formerly Keffer) ,  Stephen Cournane ,  Felino V. Cortez, JR. ,  Nancy Ling Chung ,  Daniel Yasevac ,  Andrew Ryan ,  Slava Arabagi ,  Jaime L. Baluyot ,  Sooji Van Echten ,  Da-Yu Chang ,  John Richard Carpenter ,  Sai Prasad Uppalapati ,  Pui Tong Ho ,  Jason Thai Le ,  Adam J. Yestrepsky

IPC: A61B17/122 ,  A61B17/00 ,  A61B17/128

CPC classification number: A61B17/1227 ,  A61B17/00234 ,  A61B17/1285 ,  A61B2017/00243

Abstract: Systems, apparatuses, and methods disclosed herein may be directed to clips for medical implementation, including clips for a portion of a heart. The clips may be configured to close the portion of the heart, to reduce blood flow therethrough as well as passage of clots or other undesired materials. In examples, the clips may be configured to close the left atrial appendage (LAA). The closure of the LAA may reduce the possibility of stroke or other maladies stemming from fluid flow with the LAA. In examples, the clips may be positioned exterior of the LAA, to extend over an outer surface of the LAA for closure.

公开(公告)号：US20220000618A1

公开(公告)日：2022-01-06

申请号：US17479225

申请日：2021-09-20

Applicant: Edwards Lifesciences Corporation

Inventor： Brian C. Gray ,  Tung T. Le ,  Andrew Oien ,  Sonny Tran ,  Thanh Huy Le ,  Robert Bowes ,  Maria L. Saravia ,  Uy D. Trinh ,  Hamid Rafi ,  Alejandro J. Froimovich Rosenberg

IPC: A61F2/24

Abstract: Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

公开(公告)号：US10154904B2

公开(公告)日：2018-12-18

申请号：US14695607

申请日：2015-04-24

Applicant: Edwards Lifesciences Corporation

Inventor： Brian C. Gray ,  Tung T. Le ,  Andrew Oien ,  Sonny Tran ,  Thanh Huy Le ,  Robert Bowes ,  Maria L. Saravia ,  Uy D. Trinh ,  Hamid Rafi ,  Alejandro J. Froimovich Rosenberg

IPC: A61F2/24 ,  A61F2/962 ,  A61F2/95

Abstract: Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

公开(公告)号：US20150305863A1

公开(公告)日：2015-10-29

申请号：US14695607

申请日：2015-04-24

Applicant: Edwards Lifesciences Corporation

Inventor： Brian C. Gray ,  Tung T. Le ,  Andrew Oien ,  Sonny Tran ,  Thanh Huy Le ,  Robert Bowes ,  Maria L. Saravia ,  Uy D. Trinh ,  Hamid Rafi ,  Alejandro J. Froimovich Rosenberg

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/962 ,  A61F2002/9517

Abstract: Disclosed embodiments of introducer devices provide hemostatic sealing and allow a delivery catheter to be inserted through the introducer seals without the use of a separate loader device that covers a medical device that is mounted on the catheter. Some disclosed introducers comprise a housing, a distal sheath extending distally from the housing and adapted to be inserted into a patient's vasculature, a distal hemostatic seal mounted within the housing and a proximal hemostatic seal mounted within the housing, and a slidable tube positioned within the housing that is movable longitudinally relative to the distal hemostatic seal between a proximal position and a distal position, wherein in the proximal position a distal end of the tube is positioned proximal to the distal hemostatic seal with the distal hemostatic seal closed, and wherein in the distal position the distal end of the tube extends through the distal hemostatic seal.

Abstract translation: 导引器装置的公开的实施例提供止血密封，并且允许输送导管插入通过导引器密封件，而不使用覆盖安装在导管上的医疗装置的单独的装载器装置。 一些公开的导引器包括壳体，远端护套，其从壳体向远侧延伸并适于插入患者的脉管系统中，安装在壳体内的远端止血密封件和安装在壳体内的近端止血密封件，以及位于壳体内部的可滑动管 壳体，其相对于近端位置和远端位置之间的远端止血密封件纵向移动，其中在近侧位置，所述管的远端位于所述远端止血密封件的近侧，所述远端止血密封件封闭，并且其中 远端位置，管的远端延伸穿过远端止血密封。