公开(公告)号：US09827093B2

公开(公告)日：2017-11-28

申请号：US14278594

申请日：2014-05-15

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  M. Sean McBrayer

IPC: A61F2/06 ,  A61F2/24 ,  A61F2/95 ,  A61F2/966

CPC classification number: A61F2/2418 ,  A61B5/021 ,  A61B5/026 ,  A61B5/6862 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/844 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2002/9665 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2250/0006 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065 ,  A61F2250/0069

Abstract: A method for implanting a stent includes contracting a self-expanding/forcibly-expanding stent of a shape-memory material set to a given shape to a reduced implantation size with a delivery system having drive wires. The stent has a selectively adjustable assembly with adjustable elements operatively connected to the drive wires such that, when the adjustable elements are adjusted by the drive wires, a configuration change in at least a portion of the self-expanding stent occurs. The contracted stent is inserted into a native annulus in which the stent is to be implanted. The drive wires are rotated with the delivery system to forcibly expand the stent into the native annulus. While rotating the drive wires, a torque applied to the drive wires is determined with the delivery system. Rotation of the drive wires is stopped based upon a value of the determined torque.

公开(公告)号：US09566178B2

公开(公告)日：2017-02-14

申请号：US13656717

申请日：2012-10-21

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Max Pierre Mendez ,  Korey Kline ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Derek Dee Deville

IPC: A61F2/06 ,  A61F2/966 ,  A61F2/24 ,  A61F2/07 ,  A61F2/958 ,  A61F2/848 ,  A61F2/95

CPC classification number: A61F2/243 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0091 ,  A61F2230/0054 ,  A61F2250/0006 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/006

Abstract: Sealable and repositionable implant devices are provided with features that increase the ability of implants such as endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and/or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes an implant body and a selectively adjustable assembly attached to the implant body, the assembly having adjustable elements and being operable to cause a configuration change in a portion of the implant body and, thereby, permit implantation of the implant body within an anatomic orifice to effect a seal therein under normal physiological conditions.

Abstract translation: 可密封和可重新定位的植入装置具有增加诸如血管内移植物和瓣膜的植入物精确部署或重新部署的能力的特征，具有更好的原位适应目标受体解剖部位的局部解剖结构和/或与 部署后调整能力以适应可能损害植入物功效的解剖变化。 手术植入物包括植入物主体和附接到植入物主体的选择性可调节组件，该组件具有可调节元件并且可操作以在植入物本体的一部分中引起构型改变，从而允许植入物本体内植入 解剖孔口，以在正常生理条件下进行密封。

公开(公告)号：US11707356B2

公开(公告)日：2023-07-25

申请号：US17118382

申请日：2020-12-10

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  M. Sean McBrayer

IPC: A61F2/24 ,  A61F2/95 ,  A61B5/00 ,  A61F2/844 ,  A61B5/021 ,  A61B5/026 ,  A61F2/966

CPC classification number: A61F2/2418 ,  A61B5/6862 ,  A61F2/243 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/844 ,  A61F2/95 ,  A61B5/021 ,  A61B5/026 ,  A61F2/2427 ,  A61F2/9517 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9534 ,  A61F2002/9665 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2250/001 ,  A61F2250/0006 ,  A61F2250/006 ,  A61F2250/0007 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0065 ,  A61F2250/0069

Abstract: A prosthetic heart valve includes a frame, a valve, and an expansion element. The frame is movable between contracted and expanded configurations and includes first struts and second struts non-hingedly coupled together. The second struts are configured to pivot relative to the first struts as the frame moves between the contracted and expanded configurations. The valve is coupled to the frame and includes leaflets. The expansion element extends through a lumen of the first struts. The expansion element is slidable relative to the lumen of the first struts and is configured to move the frame incrementally from the contracted configuration and the expanded configuration and from the expanded configuration to the contracted configuration.

公开(公告)号：US09913716B2

公开(公告)日：2018-03-13

申请号：US15414239

申请日：2017-01-24

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Max Pierre Mendez ,  Korey Kline ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Derek Dee Deville

IPC: A61F2/24 ,  A61F2/966 ,  A61F2/07 ,  A61F2/958 ,  A61F2/06 ,  A61F2/848 ,  A61F2/95

CPC classification number: A61F2/243 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0091 ,  A61F2230/0054 ,  A61F2250/0006 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/006

Abstract: A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

公开(公告)号：US20190216622A1

公开(公告)日：2019-07-18

申请号：US16359548

申请日：2019-03-20

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  M. Sean McBrayer

IPC: A61F2/93 ,  A61F2/844 ,  A61F2/24 ,  A61F2/82 ,  A61F2/07

CPC classification number: A61F2/93 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2/82 ,  A61F2/844 ,  A61F2002/075 ,  A61F2002/825 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9534 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0007 ,  A61F2250/0008 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065

Abstract: A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve. The handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold.

公开(公告)号：US09814611B2

公开(公告)日：2017-11-14

申请号：US13772203

申请日：2013-02-20

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC: A61F2/82 ,  A61F2/93 ,  A61F2/07 ,  A61F2/24 ,  A61F2/95

CPC classification number: A61F2/93 ,  A61F2/07 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2439 ,  A61F2/82 ,  A61F2002/075 ,  A61F2002/825 ,  A61F2002/9511 ,  A61F2002/9534 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2250/0007 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/006 ,  A61F2250/0065

Abstract: Sealable and repositionable implant devices are provided to increase the ability of endovascular grafts and valves to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant. A surgical implant includes a self-expanding stent of a shape-memory material set to a given shape. The stent has a wall with a portion having a first thickness and a second portion having a thickness greater than the first. The second portion defines a key-hole shaped longitudinal drive orifice. The implant includes a selectively adjustable assembly having adjustable elements and being operable to force a configuration change in at least a portion of the self-expanding stent. The adjustable elements have a part rotatably disposed within the longitudinal drive orifice.

公开(公告)号：US20210205079A1

公开(公告)日：2021-07-08

申请号：US17118382

申请日：2020-12-10

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  M. Sean McBrayer

IPC: A61F2/24 ,  A61F2/95 ,  A61B5/00 ,  A61F2/844

Abstract: A prosthetic heart valve includes a frame, a valve, and an expansion element. The frame is movable between contracted and expanded configurations and includes first struts and second struts non-hingedly coupled together. The second struts are configured to pivot relative to the first struts as the frame moves between the contracted and expanded configurations. The valve is coupled to the frame and includes leaflets. The expansion element extends through a lumen of the first struts. The expansion element is slidable relative to the lumen of the first struts and is configured to move the frame incrementally from the contracted configuration and the expanded configuration and from the expanded configuration to the contracted configuration.

公开(公告)号：US10980650B2

公开(公告)日：2021-04-20

申请号：US16359548

申请日：2019-03-20

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  M. Sean McBrayer

IPC: A61F2/24 ,  A61F2/93 ,  A61F2/844 ,  A61F2/07 ,  A61F2/82 ,  A61F2/95

Abstract: A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve. The handle is configured for actuating the actuation mechanism, tracking a response of native tissue when the prosthetic heart valve is in contact with the native tissue, and stopping expansion of the prosthetic heart valve once a rate of change of expansion of the prosthetic heart valve declines below a threshold.

公开(公告)号：US10478295B2

公开(公告)日：2019-11-19

申请号：US15918987

申请日：2018-03-12

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard George Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Max Pierre Mendez ,  Korey Kline ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Derek Dee Deville

IPC: A61F2/24 ,  A61F2/966 ,  A61F2/95 ,  A61F2/07 ,  A61F2/958 ,  A61F2/06 ,  A61F2/848

Abstract: A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor. The rotatable drive shaft can have a proximal end portion and a distal end portion. The proximal end portion of the rotatable drive shaft can be coupled to the motor, and the distal end portion of the rotatable drive shaft can be configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism can be configured to control and monitor expansion of the prosthetic heart valve and to control and monitor torque of the motor.

公开(公告)号：US10238514B2

公开(公告)日：2019-03-26

申请号：US15793867

申请日：2017-10-25

Applicant: Edwards Lifesciences CardiAQ LLC

Inventor： Richard Cartledge ,  Kevin W. Smith ,  Thomas O. Bales, Jr. ,  Derek Dee Deville ,  Korey Kline ,  Max Pierre Mendez ,  Matthew A. Palmer ,  Michael Walter Kirk ,  Carlos Rivera ,  Eric Petersen ,  Sean McBrayer

IPC: A61F2/24 ,  A61F2/966 ,  A61F2/93 ,  A61F2/844 ,  A61F2/07 ,  A61F2/82 ,  A61F2/95

Abstract: A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display. The actuation mechanism includes a motor and one or more actuators. The rotatable drive shaft has a proximal end portion and a distal end portion. The proximal end portion is coupled to the motor, and the distal end portion is configured to be releasably coupled to a prosthetic heart valve. The actuation mechanism is configured to control and monitor expansion of the prosthetic heart valve, and the display is configured to display a diameter of the prosthetic heart valve.