专利检索 ap:("Edgewise Therapeutics, Inc.") AND inv:"Alan James Russell" 第 1 页

1.

发明公开
PYRIDAZINONE COMPOUNDS AND USES THEREOF 审中-公开

公开(公告)号：US20240336609A1

公开(公告)日：2024-10-10

申请号：US18666699

申请日：2024-05-16

申请人： Edgewise Therapeutics, Inc.

发明人： Kevin Koch , Natalie Anne Hawryluk , Stephen Thomas Schlachter , Alan James Russell

IPC分类号： C07D417/14 , A61K31/4439 , A61K31/444 , A61K31/501 , A61K31/5377 , C07D417/04

CPC分类号： C07D417/14 , A61K31/4439 , A61K31/444 , A61K31/501 , A61K31/5377 , C07D417/04

摘要： Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.