公开(公告)号：US20240059690A1

公开(公告)日：2024-02-22

申请号：US17999421

申请日：2021-05-20

Applicant: ESTEVE PHARMACEUTICALS, S.A.

Inventor： Ariadna FERNANDEZ-DONIS ,  José-Luis DÍAZ-FERNÁNDEZ ,  Carmen ALMANSA-ROSALES ,  Mónica GARCIA-LOPEZ ,  Joan-Carles FERNANDEZ-COLLADO ,  Jordi GONZALEZ-GARCIA ,  Maria GARRIDO-MARTINEZ

IPC: C07D487/04 ,  A61P29/02

CPC classification number: C07D487/04 ,  A61P29/02

Abstract: The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the α2δ subunit of the voltage-gated calcium channel and the sigma-1 (σ1) receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.