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    METHOD AND APPARATUS OF ALIGNING A READ SEQUENCE
    1.
    发明申请
    METHOD AND APPARATUS OF ALIGNING A READ SEQUENCE 审中-公开
    读取序列的方法和装置

    公开(公告)号：US20140207386A1

    公开(公告)日：2014-07-24

    申请号：US13940182

    申请日：2013-07-11

    Applicant: Electronics and Telecommunications Research Institute

    Inventor： Ho-Youl JUNG ,  Minho KIM ,  Myung-eun LIM ,  Jae Hun CHOI ,  Soo Jun PARK

    IPC: G06F19/22

    CPC classification number: G16B30/00

    Abstract: Provided are a method of aligning a read sequence relative to a reference sequence using a seed and a read-sequence aligning apparatus using the same. The apparatus may include a seed generating unit producing seeds from read sequences, a representative seed selecting unit grouping the seeds into a plurality of seed clusters and selecting representative seeds from the plurality of seed clusters, a seed aligning unit aligning the representative seeds relative to a reference sequence, and a read-sequence aligning unit aligning the read sequences relative to the reference sequence, with reference to the alignment result of the representative seeds. The read sequence alignment may be performed using relationship between seeds, and thus, the sequencing may be performed with improved efficiency.

    Abstract translation: 提供了使用种子和使用其的读取序列对准装置使读取序列相对于参考序列对准的方法。 该装置可以包括从读取序列产生种子的种子生成单元，将种子分组成多个种子群并从多个种子群中选择代表性种子的代表种子选择单元，将代表性种子相对于 参考序列，以及读取序列对齐单元，参考代表性种子的比对结果，相对于参考序列对准读取序列。 可以使用种子之间的关系来执行读取序列比对，因此，可以以提高的效率进行测序。

    METHOD OF ANALYZING GENOME BY GENOME ANALYZING DEVICE
    3.
    发明申请
    METHOD OF ANALYZING GENOME BY GENOME ANALYZING DEVICE 审中-公开
    通过基因分析装置分析基因组的方法

    公开(公告)号：US20150199476A1

    公开(公告)日：2015-07-16

    申请号：US14597052

    申请日：2015-01-14

    Applicant: Electronics and Telecommunications Research Institute

    Inventor： Minho KIM ,  Dae Hee KIM ,  Myung-eun LIM ,  Ho-Youl JUNG

    IPC: G06F19/22

    CPC classification number: G16B30/00 ,  G16B20/00

    Abstract: Provided is a method for analyzing a genome by a genome analyzing device. The method of analyzing a genome of the present invention includes: reading sequencing data of the genome from a storage device; selecting a position to be analyzed among positions corresponding to the sequencing data; and determining a base type at the selected position by using base types and quality values of bases corresponding to the selected position among the sequencing data.

    Abstract translation: 提供了一种通过基因组分析装置分析基因组的方法。 分析本发明的基因组的方法包括：从存储装置读取基因组的测序数据; 在与排序数据相对应的位置中选择要分析的位置; 以及通过使用与所述排序数据中的所选择的位置相对应的碱基的碱基类型和质量值来确定所选位置处的碱基类型。

    NUCLEIC READS ALIGNING DEVICE AND ALIGNING METHOD THEREOF
    5.
    发明申请
    NUCLEIC READS ALIGNING DEVICE AND ALIGNING METHOD THEREOF 审中-公开
    核心读取装置及其对准方法

    公开(公告)号：US20140100789A1

    公开(公告)日：2014-04-10

    申请号：US14038456

    申请日：2013-09-26

    Applicant: Electronics and Telecommunications Research Institute

    Inventor： Jae Hun CHOI ,  Minho KIM ,  Myung-eun LIM ,  Ho-Youl JUNG ,  Soo Jun PARK

    IPC: G06F19/22

    CPC classification number: G16B30/00

    Abstract: Provided is a nucleic reads aligning method. More particularly, the present invention relates to a nucleic reads aligning method using a many-core process. A nucleic reads aligning device aligning a set of nucleic reads of a sequence to be analyzed with a reference sequence according to the present invention includes a main memory storing the reference sequence and the set of nucleic reads, a main processor splitting the reference sequence to produce first and second reference sequence fragments, and a many-core module aligning the set of nucleic reads with each of the first and second reference sequence fragments in parallel. The nucleic reads aligning device and method according to the present invention split a reference sequence and quickly align nucleic reads in a many-core environment.

    Abstract translation: 提供核酸读取对准方法。 更具体地，本发明涉及使用多核方法的核读取对准方法。 核酸读取对准装置将待分析序列的一组核酸读取与根据本发明的参考序列对准，包括存储参考序列和该组核酸读取的主存储器，分割参考序列以产生 第一和第二参考序列片段，以及多核心模块，其将所述一组核酸读取与所述第一和第二参考序列片段中的每一个平行对准。 核心读取根据本发明的对准装置和方法分割参考序列并在多核环境中快速对准核读。

    DEVICE AND METHOD OF PROCESSING MULTI-DIMENSIONAL TIME SERIES MEDICAL DATA
    6.
    发明申请
    DEVICE AND METHOD OF PROCESSING MULTI-DIMENSIONAL TIME SERIES MEDICAL DATA 审中-公开

    公开(公告)号：US20190180882A1

    公开(公告)日：2019-06-13

    申请号：US16031162

    申请日：2018-07-10

    Applicant: Electronics and Telecommunications Research Institute

    Inventor： Youngwoong HAN ,  Hwin Dol PARK ,  Myung-eun LIM ,  Ho-Youl JUNG ,  Jae Hun CHOI

    IPC: G16H50/50 ,  G06N99/00

    Abstract: Provided are a device and method for processing multi-dimensional time series medical data. The device for processing multi-dimensional time series medical data according to an embodiment of the present invention includes a network interface, a preprocessing unit, a data analysis unit, and a processor. The network interface may receive time series medical data including first visit data corresponding to the first time and second visit data corresponding to the second time before the first time. The preprocessing unit preprocesses the time series medical data to generate the modeling data. The preprocessing unit is configured to preprocess the first visit data based on a difference between the first time and the second time. The data analysis unit may generate a time series analysis model for predicting future visit data from the modeling data.

    HEALTH STATE PREDICTION SYSTEM INCLUDING ENSEMBLE PREDICTION MODEL AND OPERATION METHOD THEREOF
    9.
    发明申请
    HEALTH STATE PREDICTION SYSTEM INCLUDING ENSEMBLE PREDICTION MODEL AND OPERATION METHOD THEREOF 有权

    公开(公告)号：US20220359082A1

    公开(公告)日：2022-11-10

    申请号：US17735320

    申请日：2022-05-03

    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE

    Inventor： Myung-eun LIM ,  Do Hyeun KIM ,  Jae Hun CHOI

    IPC: G16H50/30 ,  G06N20/20

    Abstract: Disclosed is an operation method of a health state prediction system which includes an ensemble prediction model. The operation method includes sending a prediction result request for health time-series data to a plurality of external medical support systems, receiving a plurality of external prediction results associated with the health time-series data from the plurality of external medical support systems, generating long-term time-series data and short-term time-series data for each of the health time-series data, and the plurality of external prediction results, extracting a plurality of long-term trends based on the long-term time-series data, extracting a plurality of short-term trends based on the short-term time-series data, calculating external prediction goodness-of-fit based on the plurality of long-term trends and the plurality of short-term trends, and generating an ensemble prediction result based on the external prediction goodness-of-fit and the plurality of external prediction results.

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