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公开(公告)号：US20240058129A1
公开(公告)日：2024-02-22
申请号：US18112455
申请日：2023-02-21
发明人： Shaun Fetherston , Alexander H. Siemons , Blake W. Axelrod , Gil Senesh , Tomer Saar , Oren Cohen , Elazar Levi Schwarcz , Tamir S. Levi , Michael Bukin , Michael R. Bialas , Timothy A. Geiser , Sudarsan Pranatharthikaran , Carla Susana Cerqueira
CPC分类号： A61F2/2496 , A61B8/445 , A61B8/0883 , A61F2/2433 , A61B2090/064
摘要： A medical balloon sensing assembly constituted of: a handle; a first catheter extending distally from the handle; an inflatable medical balloon, the inflatable medical balloon secured by the first catheter; at least one sensor position member; and at least one sensor secured to the at least one sensor position member, wherein the at least one sensor position member is arranged to contact an outer face of the inflatable medical balloon.
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2.发明申请SYSTEMS AND METHODS FOR PLACING A COAPTING MEMBER BETWEEN VALVULAR LEAFLETS 有权用于配置瓣膜叶片之间的覆盖部件的系统和方法公开(公告)号：US20130325110A1
公开(公告)日：2013-12-05
申请号：US13895611
申请日：2013-05-16
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2424 , A61F2/2454 , A61F2/246 , A61F2/2463 , A61F2/2466 , A61F2210/0061 , A61F2230/0023 , A61F2250/0003 , A61F2250/001
摘要： The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. Finally, there is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.
摘要翻译： 本发明涉及用于改善有缺陷心脏瓣膜的功能的装置和方法，特别是涉及通过房室心脏瓣膜（即二尖瓣和三尖瓣瓣）来减少反流。 对于三尖瓣修复，该装置包括部署在右心室的组织中的锚定件，在通向右心房的孔中，或锚定到三尖瓣。 柔性锚杆连接到锚固件上，导管上的接合元件越过锚杆。 导管附接到接合元件的近端，并且锁定机构固定接合元件相对于锚固轨道的位置。 最后，有一个近端锚固特征，将接合导管的近端固定在毗邻锁骨下静脉的位置。 接合元件包括惰性覆盖物，并通过与瓣膜传递接触来帮助减少反流。
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公开(公告)号：US10667904B2
公开(公告)日：2020-06-02
申请号：US15452617
申请日：2017-03-07
发明人： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, Jr.
摘要： Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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4.发明申请公开(公告)号：US20190125232A1
公开(公告)日：2019-05-02
申请号：US15801009
申请日：2017-11-01
发明人： Jason A. Wine , Alexander H. Siemons , Andrew Nguyen Hoan , Mandana Farhadieh , Brian Patrick Murphy
摘要： Disclosed is a multi-port control valve with multi-lumen paths diverging flow so that, the multi-port control valve fills and expels fluid at the same time through the same port for use in a blood sampling, blood pressure monitoring system that includes a sampling site, a pressure transducer, and reservoir. The multi-port control valve may include a rotatable valve member and three ports. Each of the three ports is connected to one of the sampling site, the pressure transducer, and the reservoir. In particular, the rotatable valve member is rotatable, such that, depending upon a position of the rotatable valve member, one of the three ports is blocked from fluid communication with the other two ports.
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公开(公告)号：US20180289271A1
公开(公告)日：2018-10-11
申请号：US15878686
申请日：2018-01-24
IPC分类号： A61B5/0225 , A61B5/022 , A61B5/00 , A61B5/0235
摘要： Disclosed is a blood pressure measurement device that utilizing volume clamping and that is wearable by a patient. The blood pressure measurement device may comprise: a finger cuff attachable to the patient's finger including a light emitting diode (LED)-photodiode (PD) pair to measure a pleth signal and a bladder surrounding the finger and a blood pressure measurement controller coupled to the bladder through a finger cuff connector to provide pneumatic pressure to the bladder. The blood pressure measurement controller may be wearable by the patient. The blood pressure measurement controller may include: a pump coupled to the finger cuff connector, a valve, a pressure sensor, and control circuitry coupled to the pump, the valve, the pressure sensor, and the LED-PD pair.
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公开(公告)号：US20140235984A1
公开(公告)日：2014-08-21
申请号：US14168932
申请日：2014-01-30
发明人： Jennifer L. Wilbur , Michael Higgins , Paul S. Van Wieren , Alexander H. Siemons , Chris J. Okos
CPC分类号： A61B5/150992 , A61B5/14503 , A61B5/14532 , A61B5/1495 , A61B5/15003 , A61B5/150229 , A61B5/150259 , A61B5/150755 , A61B5/155 , A61B5/157 , A61B5/6866
摘要： The present invention provides a blood parameter sensing system that may include a sensor, a blood access system, a flow controller and a monitor system. The blood access system may include a blood draw member having an internal configuration adapted to avoid clotting without the use of anticoagulants and under a range of flow profiles, including small volume blood draws. The flow controller may be configured to adapt to a range of access devices by using feedback from the sensor and monitor to customize flow profiles. The monitor system is configured to reduce parameter measurement error by modeling sensitivity change during system startup or reconnect.
摘要翻译： 本发明提供一种血液参数检测系统，其可以包括传感器，血液存取系统，流量控制器和监视器系统。 血液存取系统可以包括具有适于避免凝血而不使用抗凝剂并且在一定范围的流动特征（包括小体积血液抽吸）下的内部构造的血液抽吸构件。 流量控制器可以被配置为通过使用来自传感器和监视器的反馈来适应一系列访问设备来定制流量简档。 监视器系统配置为通过在系统启动或重新连接期间建立灵敏度更改来降低参数测量误差。
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公开(公告)号：US20230210496A1
公开(公告)日：2023-07-06
申请号：US18181508
申请日：2023-03-09
发明人： Julio Agustin Isla Garcia , Rendle Lamarr Myles, JR. , Xiaolong Li , Alexander H. Siemons , Blake W. Axelrod
IPC分类号： A61B8/00
CPC分类号： A61B8/4254 , A61B8/4477 , A61B8/4455 , A61B8/54
摘要： A biomedical sensor is provided that includes a deformable body panel, a first ultrasonic transducer, a second ultrasonic transducer, and a displacement sensor. The first and second ultrasonic transducers are attached to, and the displacement sensor is in communication with, the deformable body panel. The biomedical sensor is disposable in at least one default configuration wherein the first and second ultrasonic transducers are disposed relative to one another in a known first spatial transducer configuration. The biomedical sensor is disposable in one or more deformed configurations wherein the first and second ultrasonic transducers are disposed relative to one another in a second spatial transducer configuration different than the first spatial transducer configuration. The at least one displacement sensor is configured to produce signal information indicative of a difference between the first and second spatial transducer configurations.
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公开(公告)号：US20190261872A1
公开(公告)日：2019-08-29
申请号：US16266366
申请日：2019-02-04
IPC分类号： A61B5/0225 , A61B5/022 , A61B5/026 , A61B5/00
摘要： Disclosed is a system to provide adaptive tuning through a control system to a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure in the patient's artery by a blood pressure measurement system utilizing a volume clamp method. When the finger cuff is placed around the patient's finger, the bladder and the LED-PD pair aid in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method, wherein the adaptive tuning system: applies a first pressure impulse and measures a pleth versus time response; from the pressure versus time response, determines pleth servo gains that compensate for delays in a pleth response of the finger; and uses the determined pleth servo gains in the control system in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method.
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9.发明申请公开(公告)号：US20190167195A1
公开(公告)日：2019-06-06
申请号：US16179643
申请日：2018-11-02
发明人： Blake W. Axelrod , Alexander H. Siemons , Virginia Qi Lin , Leah Paige Gaffney , Laura J. Livant
IPC分类号： A61B5/00 , A61B5/0225 , A61B5/022 , A61B5/021 , A61B5/0295 , A61B5/026
摘要： Disclosed is a system to monitor a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure by a blood pressure measurement system utilizing the volume clamp method and to measure the plethysmogram of the finger cuff. The system comprises the finger cuff that includes an enclosing portion that encloses a patient's finger. The enclosing portion includes a bladder and a light emitting diode (LED) and photodiode (PD) pair. The system further comprises a processor to: command applying pneumatic pressure to the bladder of the finger cuff from a low pressure to a high pressure; measure the plethysmogram of the finger cuff as the pressure increases from the low pressure to the high pressure; and determine fitness of the finger cuff on the patient's finger based on the measured plethysmogram. When the finger cuff is placed around the patient's finger, the bladder and the LED-PD pair aid the processor in measuring the plethysmogram.
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公开(公告)号：US20180325396A1
公开(公告)日：2018-11-15
申请号：US15955939
申请日：2018-04-18
IPC分类号： A61B5/022 , H01R13/00 , H01R13/62 , H01R43/26 , H01R13/631
CPC分类号： A61B5/02241 , A61B2562/225 , A61B2562/227 , H01R13/005 , H01R13/6205 , H01R13/631 , H01R43/26
摘要： Disclosed is a connector for a blood pressure measurement system that includes a pressure generating and regulating system and a finger cuff, in which the connector comprises: a first half portion pneumatically and electrically connected to the pressure generating and regulating system; and a second half portion fixedly attached to the finger cuff, wherein the first half portion and the second half portion are connectable in two or more orientations, and wherein the pressure generating and regulating system and the finger cuff are pneumatically and electrically connected when the first half portion and the second half portion are connected.
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