公开(公告)号：US20160290867A1

公开(公告)日：2016-10-06

申请号：US15050368

申请日：2016-02-22

申请人： Duke University

发明人： Adam Wax ,  Robert N. Graf ,  Francisco E. Robles

IPC分类号： G01J3/453 ,  G01B9/02

CPC分类号： G01J3/453 ,  G01B9/02044 ,  G01B9/02084 ,  G01B9/02087 ,  G01B9/02091 ,  G01J3/45 ,  G01J2003/4538 ,  G01N21/49

摘要： Current apparatuses and methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. In one non-limiting embodiment, multiple or dual window (DW) apparatuses and methods for reconstructing time-frequency distributions (TFDs) that applies two windows that independently determine the optical and temporal resolution is provided. For example, optical resolution is provided. For example, optical resolution may relate to scattering information about a sample, and temporal resolution may be related to absorption or depth related information. The effectiveness of the apparatuses and methods is demonstrated in simulations and in processing of measured OCT signals that contain fields which vary in time and frequency. The DW technique may yield TFDs that maintain high spectral and temporal resolution and are free from the artifacts and limitations commonly observed with other processing methods.

摘要翻译： 分光光学相干断层扫描（SOCT）信号的分析的现有装置和方法遭受时间（深度）和频率（波长）分辨率之间固有的折中。 在一个非限制性实施例中，提供了用于重建施加独立地确定光学和时间分辨率的两个窗口的时间频率分布（TFD）的多重或双窗口（DW）装置和方法。 例如，提供了光学分辨率。 例如，光学分辨率可以涉及关于样本的散射信息，并且时间分辨率可以与吸收或深度相关信息相关。 在模拟和处理包含在时间和频率上变化的场的测量的OCT信号中证明了装置和方法的有效性。 DW技术可以产生维持高光谱和时间分辨率的TFD，并且不存在通常用其它处理方法观察到的伪像和限制。

公开(公告)号：US20130176560A1

公开(公告)日：2013-07-11

申请号：US13657517

申请日：2012-10-22

申请人： Duke University

发明人： Adam Wax ,  Robert N. Graf ,  Francisco E. Robles

IPC分类号： G01J3/45

CPC分类号： G01J3/453 ,  G01B9/02044 ,  G01B9/02084 ,  G01B9/02087 ,  G01B9/02091 ,  G01J3/45 ,  G01J2003/4538 ,  G01N21/49

摘要： Current apparatuses and methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. In one non-limiting embodiment, multiple or dual window (DW) apparatuses and methods for reconstructing time-frequency distributions (TFDs) that applies two windows that independently determine the optical and temporal resolution is provided. For example, optical resolution may relate to scattering information about a sample, and temporal resolution may be related to absorption or depth related information. The effectiveness of the apparatuses and methods is demonstrated in simulations and in processing of measured OCT signals that contain fields which vary in time and frequency. The DW technique may yield TFDs that maintain high spectral and temporal resolution and are free from the artifacts and limitations commonly observed with other processing methods.

公开(公告)号：US09689745B2

公开(公告)日：2017-06-27

申请号：US15050368

申请日：2016-02-22

申请人： Duke University

发明人： Adam Wax ,  Robert N. Graf ,  Francisco E. Robles

IPC分类号： G01J3/45 ,  G01B9/02 ,  G01J3/453 ,  G01N21/49

CPC分类号： G01J3/453 ,  G01B9/02044 ,  G01B9/02084 ,  G01B9/02087 ,  G01B9/02091 ,  G01J3/45 ,  G01J2003/4538 ,  G01N21/49

摘要： Current apparatuses and methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. In one non-limiting embodiment, multiple or dual window (DW) apparatuses and methods for reconstructing time-frequency distributions (TFDs) that applies two windows that independently determine the optical and temporal resolution is provided. For example, optical resolution is provided. For example, optical resolution may relate to scattering information about a sample, and temporal resolution may be related to absorption or depth related information. The effectiveness of the apparatuses and methods is demonstrated in simulations and in processing of measured OCT signals that contain fields which vary in time and frequency. The DW technique may yield TFDs that maintain high spectral and temporal resolution and are free from the artifacts and limitations commonly observed with other processing methods.