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    2,4,7-substituted 5-hydroxy benzopyrans and esters
    1.
    发明授权
    2,4,7-substituted 5-hydroxy benzopyrans and esters 失效
    2,4,7-取代的5-羟基苯并吡喃和酯

    公开(公告)号：US3947462A

    公开(公告)日：1976-03-30

    申请号：US472243

    申请日：1974-05-22

    申请人： David Lloyd Arendsen ,  Martin Winn

    发明人： David Lloyd Arendsen ,  Martin Winn

    IPC分类号： C07C37/055 ,  C07D311/60

    CPC分类号： C07C37/055 ,  Y10S514/96

    摘要： 2,4,7-Substituted 5-hydroxy benzopyrans and dihydrobenzopyrans and their esters represented by the formulae ##SPC1##Wherein each R.sub.1 is loweralkyl, and R.sub.2 is hydrogen, loweralkanoyl or ##SPC2##With Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH.sub.2, O, S, or NR.sub.5 with R.sub.5 being hydrogen or loweralkyl, with the limitation that when X is O, S, or NR.sub.5, the sum of a and b is 3 or 4 and R.sub.4 is hydrogen or loweralkyl; and R.sub.3 is ##SPC3##With Y' being a straight or branched chain alkylene group having from 1-10 carbon atoms; and each R.sub.7, R.sub.8 and R.sub.9 are the same or different members of the group consisting of hydrogen, halo, trifluoromethyl or loweralkyl and the pharmaceutically acceptable salts thereof.

    摘要翻译： 2,4,7-取代的5-羟基苯并吡喃和二氢苯并吡喃及其由下式表示的酯其中R 1为低级烷基，R 2为氢，低级烷酰基或Y Y为具有1-8个碳原子的直链或支链亚烷基 ; a是1-4的整数; b是1-4的整数; X为CH 2，O，S或NR 5，其中R 5为氢或低级烷基，限制在X为O，S或NR 5时，a和b之和为3或4，R4为氢或低级烷基; 并且R 3为Y Y'为具有1-10个碳原子的直链或支链亚烷基; 并且每个R 7，R 8和R 9是由氢，卤素，三氟甲基或低级烷基组成的组的相同或不同的成员及其药学上可接受的盐。