公开(公告)号：US20180171323A1

公开(公告)日：2018-06-21

申请号：US15574589

申请日：2016-05-18

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： Jacob Flyvholm Cramer ,  Lene Bojsen Jensen ,  Anja Hemmingsen Kellett-Smith ,  Tove Bladt ,  Sang-Kyu Lee

IPC分类号： C12N9/96 ,  C12N1/38 ,  C12N9/88 ,  C12C5/00 ,  C12G1/022

CPC分类号： C12N9/96 ,  C12C5/00 ,  C12C5/004 ,  C12G1/0203 ,  C12G2200/15 ,  C12N1/38 ,  C12N9/88 ,  C12Y401/01005

摘要： The present disclosure provides methods, compositions, apparatuses and kits comprising ALDC enzymes having a better stability and/or activity, and, optionally, the yield of ALDC enzymes which can be recovered from microorganisms is improved. In some embodiments, the present disclosure provides methods, apparatuses, compositions and kits for the use of metal ions to increase stability and/or activity, and which further can be used to recover the enzymes from microorganisms in improved yields.

公开(公告)号：US20180142228A1

公开(公告)日：2018-05-24

申请号：US15572939

申请日：2016-05-18

申请人： DUPONT NUTRITION BIOSCIENCES APS

发明人： Jacob Flyvholm Cramer ,  Anja Hemmingsen Kellett-Smith ,  Lene Bojsen Jensen ,  Bjarne Larsen

IPC分类号： C12N9/88 ,  C12N15/75

CPC分类号： C12N9/88 ,  C12N15/75 ,  C12P21/06 ,  C12Y401/01004

摘要： The present disclosure provides methods, compositions, apparatuses and kits comprising ALDC enzymes having a better stability and activity, and which further can be recovered from microorganisms in improved yields.