公开(公告)号：US20250000814A1

公开(公告)日：2025-01-02

申请号：US18688439

申请日：2022-09-01

Applicant: DONG-A ST CO., LTD.

Inventor： Sun-Woo JANG ,  Chang-Yell SHIN ,  Hae-Sun KIM ,  Sang-Min HYUN ,  Yong-Jik KIM ,  Chang-Yong SHIN ,  Jae-Han KIM

IPC: A61K9/70 ,  A61K31/13 ,  A61K47/02 ,  A61K47/10 ,  A61K47/14

Abstract: A percutaneous absorption preparation for the treatment of dementia is disclosed. The percutaneous absorption preparation contains a support layer, a drug-containing layer, and a release layer, wherein the drug-containing layer contains memantine enanthate, a solubilizer, and a pressure-sensitive adhesive. The percutaneous absorption preparation does not form crystal precipitation, shows high skin permeability, allows easy clinical control of the usable patch area, and allows control of the absorption rate by adjusting the rate of release, thus minimizing skin irritation, and provides an economic benefit of minimal waste of the drug while also preventing overdose of the drug.