公开(公告)号：US09469623B2

公开(公告)日：2016-10-18

申请号：US14615972

申请日：2015-02-06

申请人： DAIICHI SANKYO COMPANY, LIMITED

发明人： Yoshitaka Nakamura ,  Kazutoshi Ukai ,  Takafumi Kitawaki ,  Takumi Nakajima ,  Yutaka Kitagawa ,  Yukito Furuya ,  Makoto Imai ,  Eiji Numagami ,  Masakazu Wakayama ,  Ayako Saito

IPC分类号： C07C67/343 ,  C07C211/27 ,  C07C201/16 ,  C07C253/34 ,  C07C253/30 ,  C07C227/42 ,  C07C253/10 ,  C07D319/06 ,  C07C255/47 ,  C07C201/12 ,  C07C205/50 ,  C07C229/32 ,  C07C227/04 ,  C07C67/00 ,  C07C69/608 ,  C07C253/00

CPC分类号： C07D319/06 ,  C07B2200/07 ,  C07C67/00 ,  C07C67/343 ,  C07C69/608 ,  C07C201/12 ,  C07C201/16 ,  C07C205/50 ,  C07C211/27 ,  C07C227/04 ,  C07C227/42 ,  C07C229/32 ,  C07C253/00 ,  C07C253/10 ,  C07C253/30 ,  C07C253/34 ,  C07C255/47 ,  C07C2602/20

摘要： An object of the present invention is to provide an optically active bicyclic γ-amino acid derivative in a high purity. The object can be attained by a mixture of compounds represented by the general formulas (I) and (I′), or a method for producing a compound represented by the general formula (VII) or a salt thereof via the compound (I): wherein R1 and R2 each represent a C1-6 alkyl group or the like; and R3 represents a cyano group or the like,