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公开(公告)号:US20230091067A1
公开(公告)日:2023-03-23
申请号:US17950735
申请日:2022-09-22
Applicant: Colgate-Palmolive Company
Inventor: Carlo DAEP , Carl MYERS , Gokul GOVINDARAJU , Divino RAJAH
Abstract: The disclosure relates to oral care compositions comprising guanidine in free or orally acceptable salt form and a stannous ion source (e.g., stannous fluoride) as well as to methods of using and of making these compositions.
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公开(公告)号:US20230072484A1
公开(公告)日:2023-03-09
申请号:US17894098
申请日:2022-08-23
Applicant: Colgate-Palmolive Company
Inventor: Carl MYERS , Gokul GOVINDARAJU
Abstract: This application relates to novel black translucent oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a charcoal composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号:US20240173221A1
公开(公告)日:2024-05-30
申请号:US18517201
申请日:2023-11-22
Applicant: Colgate-Palmolive Company
Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate, a taurate surfactant (e.g., sodium methyl cocoyl taurate) and more than 10% water, by weight of the composition.
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公开(公告)号:US20230039655A1
公开(公告)日:2023-02-09
申请号:US17869203
申请日:2022-07-20
Applicant: Colgate-Palmolive Company
Inventor: Dennis ZHANG , Luciana RINAUDI MARRON , Stacey LAVENDER , Gokul GOVINDARAJU , Qichao RUAN
Abstract: Disclosed herein are oral care compositions comprising hydroxyapatite and a silica abrasive as well as methods of reducing or inhibiting enamel erosion, repairing enamel erosion damage, increasing enamel microcrack resistance and/or increasing enamel microscratch resistance using these compositions.
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公开(公告)号:US20240269049A1
公开(公告)日:2024-08-15
申请号:US18436344
申请日:2024-02-08
Applicant: Colgate-Palmolive Company
Inventor: Robert D'AMBROGIO , Jean DENIS , Gokul GOVINDARAJU
CPC classification number: A61K8/21 , A61K8/24 , A61K8/44 , A61K8/466 , A61K8/602 , A61K8/731 , A61Q11/00 , A61K2800/30 , A61K2800/596
Abstract: Oral care compositions and methods of use thereof are disclosed herein. In accordance with some aspects, the oral care composition comprises from about 0.5 to about 9 wt. % of one or more surfactants; from about 0.3 to about 1 wt. % of one or more thickening agent; particles having a refractive index of from about 1.0 to about 2.5; a stannous ion source; a nitrate ion source; and a phosphate ion source, wherein the composition is substantially free of a titanium containing material, and all weight percentages are based on the total weight of the oral care composition.
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公开(公告)号:US20240180798A1
公开(公告)日:2024-06-06
申请号:US18513925
申请日:2023-11-20
Applicant: Colgate-Palmolive Company
Inventor: Diana Liceth HENAO ADLEVANKIN , Jean DENIS , Lauren EVANS , Courtney Nicole HARRIS , Robert D'AMBROGIO , Gokul GOVINDARAJU
CPC classification number: A61K8/21 , A61K8/19 , A61K8/24 , A61K8/44 , A61K8/442 , A61K8/466 , A61K8/602 , A61Q11/00 , A61K2800/30
Abstract: Aspects of the invention are directed to oral care compositions. In accordance with an aspect, provided is an oral care composition having a surfactant system comprising at least one of: (i) a non-sulfate based anionic surfactant and an amphoteric surfactant, or (ii) a nonionic surfactant and an amino acid surfactant; a stannous ion source; a nitrate ion source; and a phosphate source.
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公开(公告)号:US20240050334A1
公开(公告)日:2024-02-15
申请号:US18258267
申请日:2021-12-20
Applicant: Colgate-Palmolive Company
Inventor: Lyndsay SCHAEFFER-KORBYLO , Carl MYERS , Gokul GOVINDARAJU , Reeba PAUL
IPC: A61K8/24 , A61K8/21 , A61K8/19 , A61K8/44 , A61K33/16 , A61K33/42 , A61K47/02 , A61K47/18 , A61Q11/00
CPC classification number: A61K8/24 , A61K8/21 , A61K8/19 , A61K8/44 , A61K33/16 , A61K33/42 , A61K47/02 , A61K47/183 , A61Q11/00
Abstract: The application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride or stannous pyrophosphate, potassium salts, and an amino acid (e.g., a basic amino acid) in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. Additionally, oral care compositions described here useful in order to naturally promote nitrate reduction from the oral microbiome, which can eventually result in systemic increases of nitric oxide in blood plasma, and can form part of an overall regimen to maintain or control blood pressure. Compositions comprise stannous fluoride, stannous chloride or stannous pyrophosphate, nitric acid or a water-soluble nitrate salt such as potassium nitrate, a water-soluble alkali metal polyphosphate such as tetrasodium pyrophosphate or trisodium polyphosphate, a basic amino aid such as arginine and more than 10 wt % water.
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公开(公告)号:US20240050333A1
公开(公告)日:2024-02-15
申请号:US18258251
申请日:2021-12-21
Applicant: Colgate-Palmolive Company
Inventor: Gokul GOVINDARAJU , Carl MYERS , Lyndsay SCHAEFFER-KORBYLO
Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous pyrophosphate and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, relief from dental hypersensitivity, and to treat or reduce malodor. The compositions comprise stannous pyrophosphate, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号:US20220395443A1
公开(公告)日:2022-12-15
申请号:US17826961
申请日:2022-05-27
Applicant: Colgate-Palmolive Company
Inventor: Lyndsay SCHAEFFER-KORBYLO , Carl MYERS , Gokul GOVINDARAJU , Reeba PAUL
Abstract: In one aspect, the application relates to novel aqueous oral care compositions useful for combining and delivering potassium salts and a basic amino acid in a high-water composition, for example, to naturally promote nitrate reduction from the oral microbiome, which can result in systemic increases of nitric oxide in blood plasma and can form part of an overall regimen to maintain, reduce, treat or control systemic blood pressure.
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