公开(公告)号：US20240182876A1

公开(公告)日：2024-06-06

申请号：US18485855

申请日：2023-10-12

申请人： Codexis, Inc.

发明人： David Entwistle ,  Stephanie Forget ,  Michelle Li ,  Niusha Mahmoodi ,  Ryan Reeves ,  Ljubica Vojcic ,  Jonathan Vroom ,  David Watts ,  Leland Ken Wong

IPC分类号： C12N9/12 ,  C12N15/63

CPC分类号： C12N9/1264 ,  C12N15/63 ,  C12Y207/07031

摘要： The present invention provides engineered terminal deoxynucleotidyl transferase (TdT) polypeptides useful in template-independent polynucleotide synthesis, as well as compositions, methods of utilizing these engineered polypeptides, and polynucleotides encoding the engineered terminal deoxynucleotidyl transferases.