公开(公告)号：US20240228432A1

公开(公告)日：2024-07-11

申请号：US18421117

申请日：2024-01-24

申请人： Codagen Biosciences, Inc.

发明人： Célina REVERDY ,  Gaetan GITTON ,  Xiangying GUAN ,  Indranil ADHYA ,  Rama Krishna DUMPATI ,  Samir ROY ,  Santu CHALL ,  Anisha GHOSH ,  Gauthier ERRASTI ,  Thomas DELACROIX ,  Raj CHAKRABARTI

IPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

CPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

摘要： In one aspect, compounds modulating sirtuin activity are described herein. Sirtuin modulation by compounds described herein includes sirtuin activation and sirtuin inhibition. Modulation of sirtuin activity includes sirtuin activation and/or sirtuin inhibition. In some embodiments, a sirtuin modulating compound and/or salt thereof is of Formula I described herein.