公开(公告)号：US20240228431A1

公开(公告)日：2024-07-11

申请号：US18090953

申请日：2022-12-29

申请人： Codagen Biosciences, Inc.

发明人： Célina Reverdy ,  Gaetan Gitton ,  Xiangying Guan ,  Indranil Adhya ,  Rama Krishna Dumpati ,  Samir Roy ,  Santu Chall ,  Anisha Ghosh ,  Gauthier Errasti ,  Thomas Delacroix ,  Raj Chakrabarti

IPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

CPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

摘要： In one aspect, compounds modulating sirtuin activity are described herein. Sirtuin modulation by compounds described herein includes sirtuin activation and sirtuin inhibition. Modulation of sirtuin activity includes sirtuin activation and/or sirtuin inhibition. In some embodiments, a sirtuin modulating compound and/or salt thereof is of Formula I described herein.

公开(公告)号：US12012370B1

公开(公告)日：2024-06-18

申请号：US18090953

申请日：2022-12-29

申请人： Codagen Biosciences, Inc.

发明人： Célina Reverdy ,  Gaetan Gitton ,  Xiangying Guan ,  Indranil Adhya ,  Rama Krishna Dumpati ,  Samir Roy ,  Santu Chall ,  Anisha Ghosh ,  Gauthier Errasti ,  Thomas Delacroix ,  Raj Chakrabarti

IPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

CPC分类号： C07C235/40 ,  C07D209/82 ,  C07D213/56 ,  C07D215/50 ,  C07D223/28 ,  C07D295/155 ,  C07D333/80

摘要： In one aspect, compounds modulating sirtuin activity are described herein. Sirtuin modulation by compounds described herein includes sirtuin activation and sirtuin inhibition. Modulation of sirtuin activity includes sirtuin activation and/or sirtuin inhibition. In some embodiments, a sirtuin modulating compound and/or salt thereof is of Formula I described herein.