公开(公告)号：US20180143207A1

公开(公告)日：2018-05-24

申请号：US15821578

申请日：2017-11-22

申请人： Changhua Christian Medical Foundation Changhua Christian Hospital

发明人： CHUNG HO CHANG ,  CHIA CHU CHANG

IPC分类号： G01N33/68 ,  G01N33/70

CPC分类号： G01N33/6893 ,  G01N33/70 ,  G01N2333/4703 ,  G01N2333/76 ,  G01N2400/02 ,  G01N2440/38 ,  G01N2800/042 ,  G01N2800/347 ,  G01N2800/52

摘要： A urine biomarker is provided, and more particularly, a screening method using the urine biomarker to screen a subject having a high risk of developing diabetic nephropathy is also provided. The urine biomarker of glycosylated uromodulin can be used to detect and predict diabetic patients having a high risk of developing diabetic nephropathy more accurate and earlier than general detection methods of PCR or ACR tests, thereby the patient being screened can be treated earlier and thus prevent deterioration of the progression of chronic kidney disease, and therefore dramatically decrease the risk of death.