公开(公告)号：US11802287B2

公开(公告)日：2023-10-31

申请号：US17347221

申请日：2021-06-14

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  C12N9/22 ,  C12N15/11

CPC分类号： C12N15/82 ,  C12N9/22 ,  C12N15/111 ,  C12N15/8213 ,  C12N15/8274 ,  C12N15/8286 ,  C12N2310/20 ,  C12Y204/01012

摘要： Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.

公开(公告)号：US20210079413A1

公开(公告)日：2021-03-18

申请号：US17039434

申请日：2020-09-30

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H1/06 ,  A01H6/46

摘要： High throughput methods are described for identifying combinations of mutations that can be used to improve a phenotypic feature in an organism. Large populations of organisms (e.g., plants) containing different combinations of mutations can be assessed using the methods.

公开(公告)号：US20200299717A1

公开(公告)日：2020-09-24

申请号：US15781044

申请日：2016-12-02

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H1/04 ,  C12N15/11 ,  A01H1/02 ,  C12N9/22

摘要： Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.

公开(公告)号：US11118189B2

公开(公告)日：2021-09-14

申请号：US15781044

申请日：2016-12-02

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H1/04 ,  A01H1/02 ,  C12N9/22 ,  C12N15/11

摘要： Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.

公开(公告)号：US09101100B1

公开(公告)日：2015-08-11

申请号：US14327217

申请日：2014-07-09

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Michael F. Portereiko

IPC分类号： A01H1/04 ,  C12Q1/68 ,  C12N15/82

CPC分类号： A01H1/04 ,  C12N15/8209 ,  C12N15/8216 ,  C12N15/8217 ,  C12N15/8242 ,  C12N15/8261 ,  C12Q1/6895 ,  Y02A40/146

摘要： High throughput methods are described for identifying combinations of transgenes that can be used to improve a phenotypic feature in an organism. Large populations of organisms (e.g., plants) containing different combinations of transgenes as well as different promoter-coding sequence combinations can be assessed using the methods.

摘要翻译： 描述了用于鉴定可用于改善生物体中表型特征的转基因组合的高通量方法。 可以使用这些方法评估含有不同转基因组合以及不同启动子编码序列组合的大量生物体（例如植物）。

公开(公告)号：US20210388373A1

公开(公告)日：2021-12-16

申请号：US17347221

申请日：2021-06-14

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H1/02 ,  A01H1/04 ,  C12N9/22 ,  C12N15/11

摘要： Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.

公开(公告)号：US11773403B2

公开(公告)日：2023-10-03

申请号：US17039434

申请日：2020-09-30

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H1/06 ,  A01H6/46

CPC分类号： C12N15/8247 ,  A01H1/06 ,  A01H6/4636 ,  A01H6/4666 ,  A01H6/4678 ,  A01H6/4684 ,  C12N15/8213 ,  C12N15/8271

摘要： High throughput methods are described for identifying combinations of mutations that can be used to improve a phenotypic feature in an organism. Large populations of organisms (e.g., plants) containing different combinations of mutations can be assessed using the methods.

公开(公告)号：US20190032071A1

公开(公告)日：2019-01-31

申请号：US16077024

申请日：2017-02-08

申请人： Ceres, Inc.

发明人： Roger I. Pennell ,  Richard Hamilton ,  Delin Liang

IPC分类号： C12N15/82 ,  A01H6/46

摘要： High throughput methods are described for identifying combinations of mutations that can be used to improve a phenotypic feature in an organism. Large populations of organisms (e.g., plants) containing different combinations of mutations can be assessed using the methods.