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公开(公告)号：US11147453B2
公开(公告)日：2021-10-19
申请号：US15724003
申请日：2017-10-03
Applicant: Canon U.S.A., Inc.
Inventor： Daisuke Yamada , Jeffrey Chen , Badr Elmaanaoui
Abstract: A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αt and an axial angle αa.
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公开(公告)号：US20170167861A1
公开(公告)日：2017-06-15
申请号：US14963988
申请日：2015-12-09
Applicant: Canon U.S.A., Inc.
Inventor： Jeffrey Chen , Kenji Yamazoe
CPC classification number: G02B6/3624 , G02B6/32
Abstract: Gradient index lenses, or GRIN lenses, are useful for collimating light from a waveguide and reducing loss when coupling two fibers or coupling the fiber to other optical components. There is provided herein a method to align a GRIN lens to the distal end of an optical fiber with precise lateral alignment. The alignment occurs by: (1) rotating the fiber with respect to the lens so that the fiber is parallel with the lens, such that a light is transmitted through the fiber and then through the lens, and (2) translating the fiber laterally with respect to the lens based on the position of a circle pattern that appears on the screen after the distal end of the lens. The transmitted light is centered in the circle pattern for centered alignment or positioned at calculate distance from the center of the circle pattern for off-axis alignment.
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公开(公告)号：US20190099079A1
公开(公告)日：2019-04-04
申请号：US15724003
申请日：2017-10-03
Applicant: Canon U.S.A., Inc.
Inventor： Daisuke Yamada , Jeffrey Chen , Badr Elmaanaoui
IPC: A61B5/00
Abstract: A multimodality system includes first and second modalities, a catheter, and a processor. The catheter collects fluorescent light from a plurality of locations of a sample which has been irradiated with excitation light of the second modality; a detector detects intensity of the fluorescent light received from the plurality of locations as a function of an angle α formed between the normal to the sample surface and the optical axis of the excitation light. A processor calculates the angle α at each of the plurality of locations based on radiation of the first modality incident on the sample, and corrects the intensity of the detected fluorescent light using a calibration factor g(α). The calibration factor g(α) is a function of the angle α calculated at two or more of the plurality of locations. The angle α is composed of a transversal angle αt and an axial angle αa.
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公开(公告)号：US09869820B2
公开(公告)日：2018-01-16
申请号：US14963988
申请日：2015-12-09
Applicant: Canon U.S.A., Inc.
Inventor： Jeffrey Chen , Kenji Yamazoe
CPC classification number: G02B6/3624 , G02B6/32
Abstract: Gradient index lenses, or GRIN lenses, are useful for collimating light from a waveguide and reducing loss when coupling two fibers or coupling the fiber to other optical components. There is provided herein a method to align a GRIN lens to the distal end of an optical fiber with precise lateral alignment. The alignment occurs by: (1) rotating the fiber with respect to the lens so that the fiber is parallel with the lens, such that a light is transmitted through the fiber and then through the lens, and (2) translating the fiber laterally with respect to the lens based on the position of a circle pattern that appears on the screen after the distal end of the lens. The transmitted light is centered in the circle pattern for centered alignment or positioned at calculate distance from the center of the circle pattern for off-axis alignment.
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