公开(公告)号：US20160250631A1

公开(公告)日：2016-09-01

申请号：US15150845

申请日：2016-05-10

Applicant: CORNING INCORPORATED

Inventor： ManMan Kang ,  Wai Kin Poon

IPC: B01L3/00 ,  C12Q1/68

CPC classification number: B01L3/50851 ,  B01L3/50853 ,  B01L7/52 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/168

Abstract: A reinforced microplate has reinforcing members that enhance stiffness and minimize deformation of the microplate, especially thermally-induced deformation. The reinforcing members include dots, ribs or struts that are integrally formed on a bottom surface of the microplate. In cooperation with the reinforcing members, the microplate frame can include one or more slots that act to disrupt the effects of thermal expansion and limit thermally-induced strain. To provide enhanced sealing utility and reduce sample evaporation, each well may include a raised rim with angled transition surfaces leading to a top surface, preferably in combination with at least one elevated sealing feature extending from an upper deck surface, and being arranged between corners of the deck and the plurality of wells.

Abstract translation: 加强微孔板具有加强构件，其增强微孔板的刚度和最小化变形，特别是热诱导变形。 加强构件包括整体形成在微板的底表面上的点，肋或支柱。 与加强构件协作，微板框架可以包括一个或多个槽，其用于破坏热膨胀的影响并限制热致应变。 为了提供增强的密封效用并减少样品蒸发，每个孔可以包括凸起的边缘，其具有导向顶表面的成角度的过渡表面，优选地与从上甲板表面延伸的至少一个升高的密封特征组合，并且布置在 甲板和多个井。