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公开(公告)号：US20230144783A1
公开(公告)日：2023-05-11
申请号：US17981037
申请日：2022-11-04
申请人： CORNING INCORPORATED
CPC分类号： A61J1/1412 , B65D1/023 , B65B7/2842 , A61J2200/44
摘要： A sealed pharmaceutical container including: a shoulder; a neck extending from the shoulder; a flange extending from the neck, the flange including: an underside surface extending from the neck; an outer surface extending from the underside surface, the outer surface defining an outer diameter of the flange; and an upper sealing surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container, and a sealing assembly including: a stopper including a sealing portion extending over the upper sealing surface of the flange and covering the opening, and an insertion portion extending into the opening and in contact with the inner surface of the flange, the stopper having a first CTE; and a filler member encased within the stopper and having a second CTE, the second CTE being lower than the first CTE.
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公开(公告)号：US20230072233A1
公开(公告)日：2023-03-09
申请号：US17896850
申请日：2022-08-26
申请人： CORNING INCORPORATED
摘要： A sealed pharmaceutical container comprises a flange comprising an underside surface, an outer surface extending from the underside surface, the outer surface defining an outer radius ro of the flange; and an upper surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The upper surface comprises a sealing region extending between the opening and the outer surface and comprising a radius rsr that is less than ro. The sealed pharmaceutical container also comprises a sealing assembly comprising sealing portion in contact with the upper surface at a lower surface of the sealing portion and a cap compressing the stopper against the upper surface. After compression, the sealing portion of the stopper comprises a compressed radius rsc that is less than rsr adjacent the upper surface.
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公开(公告)号：US12090118B2
公开(公告)日：2024-09-17
申请号：US17992412
申请日：2022-11-22
申请人： CORNING INCORPORATED
CPC分类号： A61J1/1412 , A61J1/065 , A61J1/1468 , B65B7/2821 , B65D41/28
摘要： Caps for sealing assemblies for sealing glass containers and maintaining container closure integrity at −80° C. or less are disclosed. The caps include a cap skirt having an annular body and a crimp region. The crimp region is a crimpable metal. The annular body of the cap skirt has a coefficient of thermal expansion (CTE) greater than a CTE of a metal consisting of aluminum, a stiffness greater than or equal to 2 times a stiffness of the crimp region, or both. The greater CTE, stiffness, or both of the cap skirt increase the seal pressure and contact area between the stopper and glass container when cooled to −80° C. or less. The caps enable the sealing assemblies to maintain a helium leakage rate of the sealed glass container of less than or equal to 1.4×10−6 cm3/s at −80° C. or less.
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公开(公告)号：US20240345325A1
公开(公告)日：2024-10-17
申请号：US18294201
申请日：2022-07-28
申请人： CORNING INCORPORATED
发明人： William Allen Wood , Jiangtao Wu
IPC分类号： G02B6/26
CPC分类号： G02B6/262
摘要： A photonic lantern includes three or more optical fibers housed within a glass capillary, each optical fiber includes a core and a cladding. The photonic lantern tapers between a first and second end such that a diameter of the glass capillary is greater at the first end than the second end and the cladding of at least two of the three or more optical fibers comprises an up-down doped cladding doped with a dopant combination that includes an up-dopant and a down-dopant. The up-dopant increases and the down-dopant decreases the effective refractive index of the up-down doped cladding. The dopant combination decreases a material viscosity of the up-down doped cladding such that a difference in the effective refractive index between a silica cladding and the up-down doped cladding is greater in a tapered region and at the second end than at the first end.
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公开(公告)号：US20230157927A1
公开(公告)日：2023-05-25
申请号：US17992412
申请日：2022-11-22
申请人： CORNING INCORPORATED
CPC分类号： A61J1/1412 , A61J1/065 , A61J1/1468 , B65B7/2821 , B65D41/28
摘要： Caps for sealing assemblies for sealing glass containers and maintaining container closure integrity at −80° C. or less are disclosed. The caps include a cap skirt having an annular body and a crimp region. The crimp region is a crimpable metal. The annular body of the cap skirt has a coefficient of thermal expansion (CTE) greater than a CTE of a metal consisting of aluminum, a stiffness greater than or equal to 2 times a stiffness of the crimp region, or both. The greater CTE, stiffness, or both of the cap skirt increase the seal pressure and contact area between the stopper and glass container when cooled to −80° C. or less. The caps enable the sealing assemblies to maintain a helium leakage rate of the sealed glass container of less than or equal to 1.4×10−6 cm3/s at −80° C. or less.
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6.发明公开公开(公告)号：US20230145946A1
公开(公告)日：2023-05-11
申请号：US17982088
申请日：2022-11-07
申请人： CORNING INCORPORATED
发明人： Michael Patrick Carson , Dane Alphanso Christie , Galan Gregory Moore , Connor Thomas O'Malley , Adam Robert Sarafian , Robert Anthony Schaut , Mark Owen Weller , Jiangtao Wu
CPC分类号： A61J1/1412 , A61J1/065
摘要： A sealed pharmaceutical container includes a shoulder, a neck extending from the shoulder, a flange extending from the neck, and a sealing assembly. The flange includes an underside surface extending from the neck, an outer surface extending from the underside surface, the outer surface defining an outer diameter of the flange, and an upper sealing surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The sealing assembly includes a stopper and a metal-containing cap securing the stopper to the flange. The stopper includes a sealing portion extending over the upper sealing surface of the flange and covering the opening, and a rim extending at least partially along the outer surface of the flange.
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公开(公告)号：US20220339067A1
公开(公告)日：2022-10-27
申请号：US17728337
申请日：2022-04-25
申请人： CORNING INCORPORATED
IPC分类号： A61J1/14
摘要： A sealed pharmaceutical container comprises a shoulder, a neck extending from the shoulder, and a flange extending from the neck. The flange comprises an outer surface extending from the underside surface and a contact surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The contact surface comprises an outer peripheral edge disposed proximate to the outer surface of the flange. The sealed pharmaceutical container comprises a sealing assembly comprising a stopper extending over the contact surface of the flange and covering the opening, and a cap securing the stopper to the flange. The stopper comprises a sealing surface that is secured in contact with the contact surface of the flange to form a seal between the flange and the stopper. An outer peripheral edge of the sealing surface is disposed at or radially inward of the outer peripheral edge.
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