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公开(公告)号:US20240366801A1
公开(公告)日:2024-11-07
申请号:US18683962
申请日:2022-08-16
Applicant: CAMBRIDGE ENTERPRISE LIMITED
Inventor: Arnaud COMMENT , Adam GAUNT , Jennifer Sunari LEWIS , Irene MARCO-RIUS , Tian CHENG
Abstract: In a method for preparing a hyperpolarised sample, for example for a magnetic resonance procedure, a starting solution comprising alpha-ketoglutaric acid and 13C-labelled molecules is frozen to form a frozen solution. The solution is irradiated with ultraviolet and/or visible radiation, to generate free radicals. The frozen solution is then hyperpolarised by applying a magnetic field to the solution while irradiating it with frequency-modulated microwave radiation.