公开(公告)号：US11504438B2

公开(公告)日：2022-11-22

申请号：US16656417

申请日：2019-10-17

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Anupama Lakshmanan ,  Arash Farhadi ,  Suchita P. Nety ,  Raymond W. Bourdeau ,  Mikhail Shapiro

IPC: A61K49/22 ,  C07K14/195 ,  A61K49/00 ,  A61B8/08

Abstract: Gas vesicles, protein variants and related compositions methods and systems for singleplexed and/or multiplexed ultrasound imaging of a target site in which a gas vesicle provides contrast for the imaging which is modifiable by application of a selectable acoustic collapse pressure value of the gas vesicle.