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公开(公告)号：US20220324836A1
公开(公告)日：2022-10-13
申请号：US17231088
申请日：2021-04-15
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , C07D513/04
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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公开(公告)号：US11008306B2
公开(公告)日：2021-05-18
申请号：US16864825
申请日：2020-05-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , C07D513/04
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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公开(公告)号：US20230322726A1
公开(公告)日：2023-10-12
申请号：US18125826
申请日：2023-03-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , C07D513/04
CPC classification number: C07D401/14 , A61K31/517 , A61K31/549 , A61K31/5377 , A61K45/06 , C07D239/94 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
Abstract: A compound of formula I
wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.-
公开(公告)号：US09822096B2
公开(公告)日：2017-11-21
申请号：US15249710
申请日：2016-08-29
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , Heather Finlay , James Neels , Naveen Kumar Dhondi , Ashokkumar Adisechan
IPC: C07D401/14 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , C07D513/04
CPC classification number: C07D401/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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公开(公告)号：US20200255407A1
公开(公告)日：2020-08-13
申请号：US16864825
申请日：2020-05-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , C07D513/04 , C07D471/04 , C07D405/12 , C07D239/94 , A61K45/06 , A61K31/549 , A61K31/5377 , A61K31/517 , C07D417/14 , C07D417/12 , C07D413/14 , C07D407/12 , C07D403/12 , C07D403/04 , C07D401/12 , C07D239/95
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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Patent Agency Ranking
公开(公告)号：US20190144426A1
公开(公告)日：2019-05-16
申请号：US16243400
申请日：2019-01-09
Applicant: Bristol-Myers Squibb Company
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , A61K31/5377 , C07D239/95 , C07D513/04 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , A61K31/517 , C07D417/14 , C07D417/12 , C07D413/14 , C07D407/12 , C07D403/12 , C07D403/04 , C07D401/12 , A61K31/549
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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公开(公告)号：US09050345B2
公开(公告)日：2015-06-09
申请号：US14200055
申请日：2014-03-07
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Heather Finlay , Ashok Kumar Adisechan , Naveen Kumar Dhondi , Kavitha Govindrajulu , Prashantha Gunaga , John Lloyd , Pothukanuri Srinivasu
IPC: C07D487/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , A61K31/53 , A61P9/06 , A61P9/04 , C07D405/04 , C07D405/14 , C07D413/04 , C07D413/14 , C07D417/04 , A61K31/5377 , C07D519/00
CPC classification number: A61K31/5377 , A61K31/53 , C07D487/04 , C07D519/00
Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, maintaining normal sinus rhythm, IKur-associated disorders, and other disorders mediated by ion channel function.
Abstract translation: 其中A，R1，R3和R24的式（I）化合物在此描述。 该化合物可用作钾通道功能的抑制剂和治疗心律不齐，维持正常窦性心律，IKur相关疾病以及由离子通道功能介导的其它病症。
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公开(公告)号：US20140256719A1
公开(公告)日：2014-09-11
申请号：US14200055
申请日：2014-03-07
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Heather Finlay , Ashok Kumar Adisechan , Naveen Kumar Dhondi , Kavitha Govindrajulu , Prashantha Gunaga , John Lloyd , Pothukanuri Srinivasu
IPC: A61K31/5377 , C07D487/04 , A61K31/53
CPC classification number: A61K31/5377 , A61K31/53 , C07D487/04 , C07D519/00
Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, maintaining normal sinus rhythm, IKur-associated disorders, and other disorders mediated by ion channel function.
Abstract translation: 其中A，R1，R3和R24的式（I）化合物在此描述。 该化合物可用作钾通道功能的抑制剂和治疗心律不齐，维持正常窦性心律，IKur相关疾病以及由离子通道功能介导的其它病症。
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公开(公告)号：US10676460B2
公开(公告)日：2020-06-09
申请号：US16243400
申请日：2019-01-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James A. Johnson , John Lloyd , Heather Finlay , James Neels , Naveen Kumar Dhondi , Prashantha Gunaga , Abhisek Banerjee , Ashokkumar Adisechan
IPC: C07D401/14 , C07D239/95 , C07D401/12 , C07D403/04 , C07D403/12 , C07D407/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K31/517 , A61K31/5377 , A61K31/549 , A61K45/06 , C07D239/94 , C07D405/12 , C07D471/04 , C07D513/04
Abstract: A compound of formula I wherein A, X, Y, Z, R1 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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公开(公告)号：US09458133B2
公开(公告)日：2016-10-04
申请号：US14771902
申请日：2014-03-10
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Heather Finlay , Ashok Kumar Adisechan , Naveen Kumar Dhondi , Prashantha Gunaga , John Lloyd , Srinivasu Pothukanuri
IPC: C07D217/12 , C07D401/04 , C07D405/04 , A61K31/4709 , C07D401/12 , C07D401/14 , C07D405/14 , C07D405/12 , A61K31/4725 , A61K31/497 , A61K31/5377 , C07D417/14
CPC classification number: C07D401/12 , A61K31/4725 , A61K31/497 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D417/14
Abstract: A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
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