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公开(公告)号:US08735398B2
公开(公告)日:2014-05-27
申请号:US13670691
申请日:2012-11-07
Applicant: Bristol-Myers Squibb Company
Inventor: Omar D. Lopez , Denis R. St. Laurent , Jason Goodrich , Jeffrey Lee Romine , Michael Serrano-Wu , Fukang Yang , Ramesh Kakarla , Xuejie Yang , Yuping Qiu , Lawrence B. Snyder
IPC: C07D249/08 , C07D231/12 , C07D413/14 , C07D233/58 , A61K31/4196 , A61K31/4245 , A61K31/415
CPC classification number: A61K31/415 , A61K31/4196 , A61K31/4245 , C07D231/12 , C07D233/58 , C07D233/64 , C07D249/06 , C07D249/08 , C07D249/12 , C07D263/32 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein.
Abstract translation: 本公开一般涉及抗病毒化合物,更具体地涉及可以抑制由丙型肝炎病毒(HCV)编码的NS5A蛋白的功能的化合物,包含这些化合物的组合物,以及用于抑制NS5A蛋白功能的方法。
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公开(公告)号:US20130085147A1
公开(公告)日:2013-04-04
申请号:US13670691
申请日:2012-11-07
Applicant: Bristol-Myers Squibb Company
Inventor: Omar D. Lopez , Denis R. St. Laurent , Jason Goodrich , Jeffrey Lee Romine , Michael Serrano-Wu , Fukang Yang , Ramesh Kakarla , Xuejie Yang , Yuping Qiu , Lawrence B. Snyder
IPC: C07D471/04 , C07D249/12 , C07D417/14 , C07D403/14 , C07D263/32 , C07D413/14
CPC classification number: A61K31/415 , A61K31/4196 , A61K31/4245 , C07D231/12 , C07D233/58 , C07D233/64 , C07D249/06 , C07D249/08 , C07D249/12 , C07D263/32 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein.
Abstract translation: 本公开一般涉及抗病毒化合物,更具体地涉及可以抑制由丙型肝炎病毒(HCV)编码的NS5A蛋白的功能的化合物,包含这些化合物的组合物,以及用于抑制NS5A蛋白功能的方法。
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