公开(公告)号：US12214296B2

公开(公告)日：2025-02-04

申请号：US18165246

申请日：2023-02-06

Applicant: Biotage AB

Inventor： Geoff Davies ,  Adam Senior ,  Lee Williams ,  Rhys Jones

IPC: B01D15/12 ,  B01D15/20 ,  B01J20/04 ,  B01J20/08 ,  B01J20/10 ,  B01J20/281 ,  B01J20/283 ,  B01J20/284 ,  B01J20/286 ,  B01L3/02 ,  G01N1/40 ,  G01N30/52 ,  G01N30/60

Abstract: The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

公开(公告)号：US11617968B2

公开(公告)日：2023-04-04

申请号：US16642474

申请日：2018-10-17

Applicant: Biotage AB

Inventor： Geoff Davies ,  Adam Senior ,  Lee Williams ,  Rhys Jones

IPC: B01D15/12 ,  B01D15/20 ,  B01J20/04 ,  B01J20/08 ,  B01J20/10 ,  B01J20/281 ,  G01N30/52 ,  G01N30/60 ,  B01L3/02 ,  G01N1/40

Abstract: The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

公开(公告)号：US20230191281A1

公开(公告)日：2023-06-22

申请号：US18165246

申请日：2023-02-06

Applicant: Biotage AB

Inventor： Geoff DAVIES ,  Adam Senior ,  Lee Williams ,  Rhys Jones

IPC: B01D15/12 ,  B01D15/20 ,  B01J20/04 ,  B01J20/08 ,  B01J20/10 ,  B01L3/02 ,  G01N1/40 ,  G01N30/52 ,  G01N30/60

CPC classification number: B01D15/125 ,  B01D15/20 ,  B01J20/04 ,  B01J20/08 ,  B01J20/103 ,  B01L3/02 ,  G01N1/405 ,  G01N30/52 ,  G01N30/6069 ,  B01L2300/069 ,  B01L2300/0681 ,  B01L2300/0832

Abstract: The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

公开(公告)号：US10112177B2

公开(公告)日：2018-10-30

申请号：US14780307

申请日：2014-03-26

Applicant: Biotage AB

Inventor： Ecevit Yilmaz ,  David Nivhede ,  Johan Billing ,  Markus Rudolfsson ,  Mats Leeman ,  Adam Senior

IPC: C02F1/28 ,  B01D15/00 ,  C02F1/68 ,  B01J20/26 ,  C08F271/02 ,  C08F291/00 ,  C08F226/00 ,  B01J20/32 ,  B01J20/30 ,  B01J20/28 ,  B01D15/20 ,  C02F1/00 ,  C02F5/08 ,  C02F5/10 ,  B01D15/02 ,  G01N1/40 ,  G01N30/00

Abstract: The present invention relates to a sorbent for extracting polar components from a sample where the sorbent comprises a cross-linked polymer comprising nitrogen containing cyclic compounds, for example 1-vinylimidazole and/or 4-vinylpyridine. The invention further relates to a method of producing said sorbent and the use of the sorbent.