公开(公告)号：US20210355521A1

公开(公告)日：2021-11-18

申请号：US16345700

申请日：2018-12-21

Applicant: Bioacts Corporation

Inventor： Jin Woo PARK ,  Jae-Ho CHOI ,  Bongkyu LEE ,  Hyoung Su KIM ,  Kiwon KIM ,  Jae-Sung LEE ,  Hyo Sung JEON ,  Sora YUN

IPC: C12Q1/14 ,  C09B29/30 ,  C09B29/46 ,  C09B29/02 ,  C12Q1/6844 ,  G01N33/84

Abstract: Provided is a diagnostic kit for determining infection with Methicillin-Resistant Staphylococcus aureus (MRSA) in a specimen, and a method for determining the infection with MRSA using the diagnostic kit is performed by visually observing a color change after LAMP reaction, and the color change is caused by a change in a magnesium concentration and confirmed using a specific dye compound which sensitively reacts with magnesium ions. The amplification of the MRSA DNA is performed using the loop-mediated isothermal amplification (LAMP), so that the diagnostic kit has advantages of being conveniently used anytime and anywhere and quickly diagnosing.

公开(公告)号：US20220229063A1

公开(公告)日：2022-07-21

申请号：US17536035

申请日：2021-11-28

Applicant: Bioacts Corporation

Inventor： Jin Woo PARK ,  Kiwon KIM ,  Gyeong Rim SHIN ,  Eunseo YU

IPC: G01N33/58 ,  C09B23/10 ,  C09B23/06 ,  C09B23/08

Abstract: A fluorescent compound in accordance with exemplary embodiments of the present invention has high stability under a water-soluble condition to be easily stored for a long time and improve pH stability and can be more efficiently used for labeling and dyeing of a target material by introducing the triazine substituted with a hydroxyl group as a linker to improve the fluorescent intensity even at a low concentration as compared with the conventional structure. Further, the fluorescent compound is excellent in optical stability and exhibits stable fluorescence in long-term dyeing, and is excellent in fluorescence intensity while being not accumulated in the body, and thus, can be easily dyed and imaged in vivo even in the use of a small amount as compared with the conventional dyes to be economically used.

公开(公告)号：US20220228985A1

公开(公告)日：2022-07-21

申请号：US17151680

申请日：2021-01-19

Applicant: Bioacts Corporation

Inventor： Jin Woo PARK ,  Kiwon KIM ,  HyungJun YOON ,  Eunae JEONG ,  Hyejin JIN ,  Yoeseph CHO

IPC: G01N21/64 ,  C09K11/06

Abstract: Disclosed is a fluorescent composition for whole blood analysis capable of predicting the diagnosis, treatment and prognosis of diseases through blood analysis. in the case of using the fluorescent composition of exemplary embodiments of the present invention for whole blood analysis, the shape of a target material such as red blood cells and white blood cells may be maintained as it is and non-target biomaterials and the like may be dissolved to increase the sensitivity and affinity to the target and improve the staining efficiency of the blood cell nucleic acids, thereby increasing the fluorescent efficiency. Therefore, more accurate blood cell analysis is possible than conventional techniques, and through this, it is possible to accurately predict not only the diagnosis of the disease, but also the treatment method and prognosis.