公开(公告)号：US12201974B2

公开(公告)日：2025-01-21

申请号：US16984852

申请日：2020-08-04

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Yochanan Uri ,  Itay Barak ,  Robert Lovchik ,  David P. Taylor ,  Marcel Buerge ,  Govind V. Kaigala

IPC: B01L3/00

Abstract: The present disclosure is notably directed to a microfluidic probe head (202), or MFP head, comprising a processing surface (204) having liquid injection and liquid aspiration apertures, as well as projections (205) extending from the processing surface (204). The arrangement of injection and aspiration apertures provides for a hydrodynamic flow confinement within a processing region that is formed between the processing surface (204) and a substrate (104) or sample surface (for example, the bottom of a microtiter plate sample well (102)), typically located beneath the processing surface (204). The disclosure is further directed to related microfluidic probe devices, and methods of operation of such an MFP head, notably to deposit cells on a surface.