专利检索 ap:("Beth Israel Deaconess Medical Center, Inc.") AND inv:"Mark Justin Iampietro" 第 1 页

1.

发明授权
Recombinant adenoviruses and uses thereof 有权

公开(公告)号：US11773142B2

公开(公告)日：2023-10-03

申请号：US16772045

申请日：2018-12-11

申请人： Beth Israel Deaconess Medical Center, Inc.

发明人： Dan H. Barouch , Peter Abbink , Mark Justin Iampietro , Menzo J. E. Havenga

IPC分类号： C07K14/075 , A61K35/761 , A61K39/235 , A61K31/7088 , C07K14/54 , C12N15/861

CPC分类号： C07K14/075 , A61K31/7088 , A61K35/761 , A61K39/235 , C07K14/5425 , C12N15/861

摘要： Featured are recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are simian (rhesus) adenoviruses having a low seroprevalence and high immunogenicity (when expressing, e.g., an antigenic polypeptide) relative to other adenoviruses and vectors thereof. Also featured are methods for producing the adenoviruses and methods of treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).