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公开(公告)号：US11724023B2
公开(公告)日：2023-08-15
申请号：US17900696
申请日：2022-08-31
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
CPC classification number: A61M5/007 , A61J1/2096 , A61K51/1213 , A61K51/1251 , A61M5/1785 , A61M5/19 , A61M5/3294 , A61N5/1007 , A61N5/1027 , A61N5/1031 , A61M2205/583 , A61M2210/1007 , A61N2005/1098
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US20230355223A1
公开(公告)日：2023-11-09
申请号：US17999376
申请日：2021-05-20
Inventor： J. Christopher Flaherty , Antonino Amato , Jason Schense , Massimo Romanelli , Maria L. Constantino , Francesco de Gaetano , Kasra Osouli
CPC classification number: A61B17/00491 , A61M5/008 , A61M5/14546
Abstract: The present disclosure relates generally to methods and apparatus to control delivery of a sealant during an invasive procedure. Disclosed methods and apparatus control movement of a syringe to control injection of sealant stored therein. For example, disclosed methods and apparatus can displace the syringe body relative to the plunger as the syringe is withdrawn from the target site, rather than displacing the plunger relative to the syringe body, to thereby pressurize the sealant or inject the sealant in an amount proportional to a distance the syringe body is withdrawn. This reduces the variability in the amount of sealant delivered along the syringe withdrawal pathway. The disclosed methods and apparatus can increase precision in movement of a syringe, thereby increasing precision in sealant delivery.
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公开(公告)号：US20220387733A1
公开(公告)日：2022-12-08
申请号：US17773544
申请日：2020-10-31
Applicant: BetaGlue Technologies S.p.A.
Inventor： Marco D'Arienzo , Giovanni Ganelli , Antonino Amato
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US20220096734A1
公开(公告)日：2022-03-31
申请号：US17498744
申请日：2021-10-11
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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Patent Agency Ranking
公开(公告)号：US11141526B2
公开(公告)日：2021-10-12
申请号：US16872295
申请日：2020-05-11
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US20210128819A1
公开(公告)日：2021-05-06
申请号：US16872295
申请日：2020-05-11
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US20230414861A1
公开(公告)日：2023-12-28
申请号：US18449622
申请日：2023-08-14
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
CPC classification number: A61M5/007 , A61M5/19 , A61M5/3294 , A61M5/1785 , A61K51/1251 , A61K51/1213 , A61N2005/1098 , A61N5/1007 , A61N5/1031 , A61N5/1027 , A61M2205/583 , A61M2210/1007 , A61J1/2096
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US20230079546A1
公开(公告)日：2023-03-16
申请号：US17900696
申请日：2022-08-31
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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公开(公告)号：US11464897B2
公开(公告)日：2022-10-11
申请号：US17498744
申请日：2021-10-11
Applicant: BetaGlue Technologies S.p.A
Inventor： Antonino Amato , Giovanni Paganelli
Abstract: Systems, kits and methods for preparing an injection system and/or treating target lesions with a selective internal radiation therapy which includes a double-barrel syringe loaded with a two-component tissue glue and radioisotope loaded microspheres. The microspheres are loaded into the syringe based on the size of the target location and are administered with a needle or dual-lumen catheter. Dosing regimens for treating breast cancer lesions or surgical beds up to 130 mm in diameter and hepatocellular carcinoma lesions up to 50 mm are included.
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