-
公开(公告)号：US07820694B2
公开(公告)日：2010-10-26
申请号：US12577855
申请日：2009-10-13
申请人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
发明人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
IPC分类号： A61K31/395 , C07D215/26 , C07D215/22
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US08283362B2
公开(公告)日：2012-10-09
申请号：US13295426
申请日：2011-11-14
申请人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
发明人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
IPC分类号： A61P11/00 , A61K31/395
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US08067437B2
公开(公告)日：2011-11-29
申请号：US12885922
申请日：2010-09-20
申请人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
发明人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
IPC分类号： A61P11/00
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US07622483B2
公开(公告)日：2009-11-24
申请号：US11074400
申请日：2005-03-07
申请人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
发明人： Bernard Cuenoud , Ian Bruce , Robin A Fairhurst , David Beattie
IPC分类号： A61K31/395
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US08436017B2
公开(公告)日：2013-05-07
申请号：US13555536
申请日：2012-07-23
IPC分类号： A61K31/395 , A61P11/00
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US08796307B2
公开(公告)日：2014-08-05
申请号：US14076478
申请日：2013-11-11
IPC分类号： A61K31/395
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US20140066478A1
公开(公告)日：2014-03-06
申请号：US14076478
申请日：2013-11-11
IPC分类号： C07D215/26
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways disease.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
公开(公告)号：US07745462B2
公开(公告)日：2010-06-29
申请号：US10552023
申请日：2004-04-02
申请人： Robin Alec Fairhurst , David Andrew Sandham , David Beattie , Ian Bruce , Bernard Cuenoud , Reamonn Madden , Neil John Press , Roger John Taylor , Katharine Louise Turner , Simon James Watson
发明人： Robin Alec Fairhurst , David Andrew Sandham , David Beattie , Ian Bruce , Bernard Cuenoud , Reamonn Madden , Neil John Press , Roger John Taylor , Katharine Louise Turner , Simon James Watson
IPC分类号： A61K31/02 , C07D215/38
CPC分类号： C07D215/227 , C07D401/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要： Compounds of formula I in free or salt form, wherein —C—Y—, R1 and R2 are G have the meanings as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the β2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
摘要翻译： 游离或盐形式的式I化合物，其中-C-Y-，R 1和R 2为G具有本说明书中指出的含义，可用于治疗通过活化2-肾上腺素受体而预防或缓解的病症 。 还描述了含有化合物的药物组合物和制备该化合物的方法。
-
公开(公告)号：US20070066607A1
公开(公告)日：2007-03-22
申请号：US10552023
申请日：2004-04-02
申请人： Robin Fairhurst , David Sandham , David Beattie , Ian Bruce , Bernard Cuenoud , Reamonn Madden , Neil Taylor , Roger Taylor , Katharine Turner , Simon Watson
发明人： Robin Fairhurst , David Sandham , David Beattie , Ian Bruce , Bernard Cuenoud , Reamonn Madden , Neil Taylor , Roger Taylor , Katharine Turner , Simon Watson
IPC分类号： A61K31/541 , A61K31/5377 , A61K31/538 , A61K31/496 , A61K31/4709 , C07D265/36 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号： C07D215/227 , C07D401/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要： Compounds of formula I free or salt form, wherein —C—Y—, R1 and R2 are G have the meanings as indicated in the specification, are useful for treating conditions that are prevented or alleviated by activation of the β2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
摘要翻译： 式I的游离或盐形式的化合物，其中-CY-，R 1和R 2是G具有说明书中指出的含义，可用于治疗 通过β2 - 肾上腺素受体的激活而被预防或缓解。 还描述了含有化合物的药物组合物和制备该化合物的方法。
-
公开(公告)号：US20120302531A1
公开(公告)日：2012-11-29
申请号：US13555536
申请日：2012-07-23
CPC分类号： A61K31/4709 , A61K45/06 , C07C215/80 , C07C233/43 , C07C311/08 , C07C2602/08 , C07D215/227 , C07D215/26 , C07D405/12
摘要： Compounds of formula in free or salt or solvate form, whereAr is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
摘要翻译： 其中Ar为式Y的化合物为碳或氮，R1，R2，R3，R4，R5，R6，R7，R8，R9，R10，X，n，p， q和r如说明书中所定义，它们的制备及其作为药物的用途，特别是用于治疗阻塞性或炎症性气道疾病。
-
-
-
-
-
-
-
-
-
搜索结果
97 条记录 (耗时 0.031 秒)
