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公开(公告)号：US20240209106A1
公开(公告)日：2024-06-27
申请号：US18513169
申请日：2023-11-17
发明人： Liang QU , Tong ZHANG , Zhuo LI , Xin CHEN , Lin ZHU , Penghao WANG , Xiaosui Zhou , Yuanyuan XIE , Jie LI , Jian SUN , Jing SONG , Xuehui LI
CPC分类号： C07K16/2878 , A61P35/00 , A61K2039/505 , C07K2317/31 , C07K2317/52 , C07K2317/565 , C07K2317/732
摘要： Provided are antigen-binding fragments thereof that bind to human CD137, multispecific antibodies that recognize CD137 as one antigen and at least one other antigen, a pharmaceutical composition comprising CD137 antibodies, and use of the antibody, multispecific antibody or the composition for treating a disease, such as cancer.
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公开(公告)号：US20240190990A1
公开(公告)日：2024-06-13
申请号：US18513255
申请日：2023-11-17
发明人： Liang QU , Zhuo LI , Liu XUE , Qi LIU , Lin ZHU , Penghao WANG , Hanzi SUN , Xiaoyan TANG
CPC分类号： C07K16/3007 , A61K45/06 , A61K47/6415 , A61P35/00 , A61K2039/505 , C07K2317/52 , C07K2317/732 , C07K2317/734
摘要： The present disclosure provides for antibodies and antigen-binding fragments thereof that bind to human CEA, a pharmaceutical composition comprising said antibody, and use of the anti-CEA antibody or the composition for treating a disease, such as cancer.
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公开(公告)号：US20240209113A1
公开(公告)日：2024-06-27
申请号：US18511764
申请日：2023-11-16
发明人： Dan LI , Xi YUAN , Jie LI , Yuanyuan XIE , Zhuo LI , Liang QU , Tong ZHANG , Jian SUN , Xuehui LI , Jing SONG , Xiaomin SONG
CPC分类号： C07K16/303 , A61P35/00 , C07K16/2878 , A61K39/00 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/622
摘要： Provided are multispecific antibodies and antigen-binding fragments thereof that bind to human GPC3 and CD137, a pharmaceutical composition comprising said antibody, and use of the multispecific antibody or the composition for treating a disease, such as cancer.
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公开(公告)号：US20240190989A1
公开(公告)日：2024-06-13
申请号：US18513223
申请日：2023-11-17
发明人： Liang QU , Tong ZHANG , Zhuo LI , Xin CHEN , Lin ZHU , Penghao WANG , Xiaosui Zhou , Yuanyuan XIE , Jie LI , Jian SUN , Jing SONG , Xuehui LI
CPC分类号： C07K16/3007 , A61P35/00 , C07K16/2878 , A61K2039/505 , C07K2317/31 , C07K2317/52 , C07K2317/565 , C07K2317/732 , C07K2317/734
摘要： Multispecific antibodies and antigen-binding fragments thereof that bind to human CEA and CD137, a pharmaceutical composition comprising said antibody, and use of the multispecific antibody or the composition for treating.
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