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    STROBED LASER EXCITATION SYSTEMS AND METHODS OF USE THEREOF
    1.
    发明申请
    STROBED LASER EXCITATION SYSTEMS AND METHODS OF USE THEREOF 有权

    公开(公告)号：US20210255089A1

    公开(公告)日：2021-08-19

    申请号：US17163870

    申请日：2021-02-01

    Applicant: Becton, Dickinson and Company

    Inventor： Pierce O. Norton ,  Geoffrey Osborne

    IPC: G01N15/14 ,  G01N21/64

    Abstract: Aspects of the present disclosure include systems for irradiating particles in a flow stream. Systems according to certain embodiments include a light source having a first laser configured for continuous irradiation of a flow stream and a second laser configured for irradiation of the flow stream in discrete intervals where each discrete interval of irradiation by the second laser is triggered by irradiation of a particle in the flow stream with the first laser. Methods for irradiating a sample in a flow stream with the subject light sources are also described. Computer readable storage medium for practicing the subject methods are provided. Kits having one or more lasers are also provided.

    Automated Set-Up for Cell Sorting
    2.
    发明申请
    Automated Set-Up for Cell Sorting 审中-公开

    公开(公告)号：US20200158545A1

    公开(公告)日：2020-05-21

    申请号：US16750726

    申请日：2020-01-23

    Applicant: Becton, Dickinson and Company

    Inventor： Pierce O. Norton ,  Vladimir Azersky

    IPC: G01F1/66 ,  G06T7/00 ,  G05D7/06 ,  G01N15/14

    Abstract: Apparatus and methods are described for automatically performing set-up steps for flow cytometry operations. The invention provides for the spatial determination of a flow stream and the subsequent automatic alignment of analysis devices and/or collection vessels. The automatic determination of flow stream properties provides for the automatic configuration flow cytometer parameters.

    Methods And Systems for Evaluating Flow Cytometer Data For The Presence of a Coincident Event
    6.
    发明公开
    Methods And Systems for Evaluating Flow Cytometer Data For The Presence of a Coincident Event 审中-公开

    公开(公告)号：US20230266228A1

    公开(公告)日：2023-08-24

    申请号：US18095130

    申请日：2023-01-10

    Applicant: Becton, Dickinson and Company

    Inventor： Pierce O. Norton

    IPC: G01N15/14

    CPC classification number: G01N15/1436 ,  G01N2015/1006

    Abstract: Methods for evaluating flow cytometer data for the presence of a coincident event are provided. Methods of interest include receiving flow cytometer data associated with a first particle, where the received flow cytometer data is obtained from a detector following the irradiation of the first particle and a second particle in a flow stream by first and second light sources, respectively. Methods also include receiving first and second trigger signals associated with the first and second particles, respectively. In addition, the subject methods include generating a time interval for the first and second particles based on a difference between the first and second trigger signals, and evaluating the flow cytometer data for the presence of a coincident event based on the generated time interval by determining if the first and second particles are irradiated by the first and second light sources simultaneously. Systems and computer-readable media are also provided.

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