公开(公告)号：US10914671B2

公开(公告)日：2021-02-09

申请号：US16390742

申请日：2019-04-22

Applicant: Becton, Dickinson and Company

Inventor： Pierce Norton ,  Kyle Dembski ,  Henry Lankila

IPC: G01N15/14

Abstract: Flow cytometers having an enclosed particle sorting module are provided. Aspects of the flow cytometers include, in addition to the enclosed particle sorting modules, a sample input module fluidically coupled to an inlet of the enclosed particle sorting module, a waste reservoir fluidically coupled to first outlet of the enclosed particle sorting module and a first sorted particle collection system fluidically coupled to a second outlet of the enclosed particle sorting module. Flow cytometers as described herein are configured to control aerosol content in the enclosed particle sorting modules, including the sort chambers of such modules. Also provided are methods of using the flow cytometers, as well as kits that include one or more components of the flow cytometers are consumables for use therewith.

公开(公告)号：US12287274B2

公开(公告)日：2025-04-29

申请号：US18203500

申请日：2023-05-30

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Kyle Dembski ,  Pierce Norton

IPC: G01N15/1404 ,  G01N15/01 ,  G01N15/14 ,  G01N15/1409

Abstract: Fluidic resistance units are provided. Fluidic resistance units of interest include a plurality of valves and a plurality of resistors, where each resistor in the plurality of resistors is fluidically coupled to and co-located with a different valve in the plurality of valves. In one embodiment, fluidic resistance units include an inlet for receiving fluid, a valve line fluidically coupled to the inlet, a resistor line fluidically coupled to the inlet, a plurality of connectors fluidically coupling the valve line to the resistor line, and an outlet for emitting fluid. Valve lines of interest include a series of fluidically coupled valves, and resistor lines of interest include a series of fluidically coupled resistors. Methods and flow cytometers involving the subject fluidic resistance units are also provided.

公开(公告)号：US20190331585A1

公开(公告)日：2019-10-31

申请号：US16390742

申请日：2019-04-22

Applicant: Becton, Dickinson and Company

Inventor： Pierce Norton ,  Kyle Dembski ,  Henry Lankila

IPC: G01N15/14

Abstract: Flow cytometers having an enclosed particle sorting module are provided. Aspects of the flow cytometers include, in addition to the enclosed particle sorting modules, a sample input module fluidically coupled to an inlet of the enclosed particle sorting module, a waste reservoir fluidically coupled to first outlet of the enclosed particle sorting module and a first sorted particle collection system fluidically coupled to a second outlet of the enclosed particle sorting module. Flow cytometers as described herein are configured to control aerosol content in the enclosed particle sorting modules, including the sort chambers of such modules. Also provided are methods of using the flow cytometers, as well as kits that include one or more components of the flow cytometers are consumables for use therewith.

公开(公告)号：US20230393047A1

公开(公告)日：2023-12-07

申请号：US18203500

申请日：2023-05-30

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Kyle Dembski ,  Pierce Norton

IPC: G01N15/14

CPC classification number: G01N15/1404 ,  G01N15/1459 ,  G01N2015/1461 ,  G01N2015/1409 ,  G01N2015/0065

Abstract: Fluidic resistance units are provided. Fluidic resistance units of interest include a plurality of valves and a plurality of resistors, where each resistor in the plurality of resistors is fluidically coupled to and co-located with a different valve in the plurality of valves. In one embodiment, fluidic resistance units include an inlet for receiving fluid, a valve line fluidically coupled to the inlet, a resistor line fluidically coupled to the inlet, a plurality of connectors fluidically coupling the valve line to the resistor line, and an outlet for emitting fluid. Valve lines of interest include a series of fluidically coupled valves, and resistor lines of interest include a series of fluidically coupled resistors. Methods and flow cytometers involving the subject fluidic resistance units are also provided.

公开(公告)号：US11441996B2

公开(公告)日：2022-09-13

申请号：US17101319

申请日：2020-11-23

Applicant: Becton, Dickinson and Company

Inventor： Pierce Norton ,  Kyle Dembski ,  Henry Lankila

IPC: G01N15/14

Abstract: Flow cytometers having an enclosed particle sorting module are provided. Aspects of the flow cytometers include, in addition to the enclosed particle sorting modules, a sample input module fluidically coupled to an inlet of the enclosed particle sorting module, a waste reservoir fluidically coupled to first outlet of the enclosed particle sorting module and a first sorted particle collection system fluidically coupled to a second outlet of the enclosed particle sorting module. Flow cytometers as described herein are configured to control aerosol content in the enclosed particle sorting modules, including the sort chambers of such modules. Also provided are methods of using the flow cytometers, as well as kits that include one or more components of the flow cytometers are consumables for use therewith.

公开(公告)号：US20210109007A1

公开(公告)日：2021-04-15

申请号：US17101319

申请日：2020-11-23

Applicant: Becton, Dickinson and Company

Inventor： Pierce Norton ,  Kyle Dembski ,  Henry Lankila

IPC: G01N15/14

Abstract: Flow cytometers having an enclosed particle sorting module are provided. Aspects of the flow cytometers include, in addition to the enclosed particle sorting modules, a sample input module fluidically coupled to an inlet of the enclosed particle sorting module, a waste reservoir fluidically coupled to first outlet of the enclosed particle sorting module and a first sorted particle collection system fluidically coupled to a second outlet of the enclosed particle sorting module. Flow cytometers as described herein are configured to control aerosol content in the enclosed particle sorting modules, including the sort chambers of such modules. Also provided are methods of using the flow cytometers, as well as kits that include one or more components of the flow cytometers are consumables for use therewith.