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公开(公告)号:US12036396B2
公开(公告)日:2024-07-16
申请号:US17194108
申请日:2021-03-05
发明人: Richard E. Cronenberg , Michael Quinn , Haiming Wu
CPC分类号: A61M5/31548 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31585 , A61M5/31595 , A61M5/24 , A61M2005/2407 , A61M5/2466 , A61M2005/2488 , A61M2005/2492 , A61M5/31543 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/3202 , A61M5/347 , A61M2205/581
摘要: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.
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公开(公告)号:US10583241B2
公开(公告)日:2020-03-10
申请号:US14888691
申请日:2014-05-02
发明人: Haiming Wu , Danial P. Ferreira
IPC分类号: A61M5/14 , A61M5/145 , A61M5/31 , A61M5/142 , A61M5/162 , A61M5/168 , B65B55/04 , A61M39/20 , A61M5/24 , A61M39/22 , A61M5/20
摘要: A drug delivery device for injecting medicament, the device including a main body having a surface for contacting a patient, an actuation button (110, 420, 436) movably disposed relative to the main body, and a reservoir disposed within the main body for containing a medicament. The device also includes a needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, wherein the lumen is fluidly connectable with the reservoir. The device further includes a removable needle cover (114, 400) for selectively covering the distal end of the needle and selectively preventing movement of the actuation button relative to the main body that initiates activation of the device.
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公开(公告)号:US20170340829A1
公开(公告)日:2017-11-30
申请号:US15669349
申请日:2017-08-04
发明人: Richard Cronenberg , Michael Quinn , Haiming Wu
IPC分类号: A61M5/315
CPC分类号: A61M5/31548 , A61M5/24 , A61M5/2466 , A61M5/31535 , A61M5/31541 , A61M5/31543 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M5/31595 , A61M5/3202 , A61M5/347 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2205/581
摘要: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.
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公开(公告)号:US10888497B2
公开(公告)日:2021-01-12
申请号:US15918166
申请日:2018-03-12
发明人: Richard A. Cronenberg , Haiming Wu
摘要: A system including an adapter for sequential engagement with a cartridge containing a first substance and a vial containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member engageable with a portion of the cartridge. A plunger rod includes a protrusion and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.
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公开(公告)号:US20180200449A1
公开(公告)日:2018-07-19
申请号:US15918166
申请日:2018-03-12
发明人: Richard A. Cronenberg , Haiming Wu
CPC分类号: A61M5/31505 , A61J1/2048 , A61M5/19 , A61M5/24 , A61M5/2448 , A61M5/31596 , A61M2005/31508 , A61M2202/064
摘要: A system including an adapter for sequential engagement with a cartridge containing a first substance and a vial containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member engageable with a portion of the cartridge. A plunger rod includes a protrusion and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.
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公开(公告)号:US09522239B2
公开(公告)日:2016-12-20
申请号:US14329753
申请日:2014-07-11
发明人: Richard Cronenberg , Haiming Wu
CPC分类号: A61M5/3158 , A61M5/31541 , A61M5/31555 , A61M5/31576 , A61M5/31581 , A61M5/31595 , A61M2005/3125 , A61M2005/3126 , A61M2205/583 , A61M2205/584
摘要: A medical injector has a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally toward a distal end of the body but not proximally toward a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger, thereby allowing the engagement portion to bypass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion.
摘要翻译: 医用注射器具有带有位移柱塞的主体。 柱塞包括沿其长度设置的多个间隔开的棘轮齿。 提供至少一个分度器以接合柱塞,其中分度器构造成允许柱塞朝向身体的远端远端移动,而不向近侧朝向身体的近端移位。 医疗注射器还包括具有形成为接合一个或多个棘齿的接合部的致动器。 致动器可移动到就绪状态,接合部分相对于柱塞向近侧位移,致动器被移位到就绪状态。 分度器防止柱塞的近端运动,从而允许接合部分绕过一个或多个棘轮齿,致动器被移动到就绪状态。 此外,致动器可从就绪状态移位以引起医用注射器的致动。 从就绪状态的位移导致接合部分的远端位移,其中接合部分接合一个或多个棘齿,并引起柱塞与接合部分的远端位移。
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公开(公告)号:US20160158435A1
公开(公告)日:2016-06-09
申请号:US14888699
申请日:2014-05-02
发明人: Haiming Wu , Danial P. Ferreira
摘要: A flow pathway subassembly (264, 278) including medicament flow pathway components of a medical device, and a holder (270, 280) configured for holding the components so that a center of gravity of the subassembly is disposed substantially on a central longitudinal axis of the subassembly.
摘要翻译: 包括医疗装置的药物流动路径部件的流动路径子组件(264,278)和构造成用于保持部件的保持器(270,280),使得子组件的重心基本上设置在 子组件。
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公开(公告)号:US20160015900A1
公开(公告)日:2016-01-21
申请号:US14377585
申请日:2013-03-08
发明人: Richard Cronenberg , Haiming Wu
CPC分类号: A61M5/31505 , A61J1/2048 , A61M5/19 , A61M5/24 , A61M5/2448 , A61M5/31596 , A61M2005/31508 , A61M2202/064
摘要: A system including an adapter (14) for sequential engagement with a cartridge (18) containing a first substance and a vial (16) containing a second substance is disclosed. The adapter is configured to first engage with the vial and subsequently engage with the cartridge such that the cartridge is in fluid communication with the vial via the adapter. The system includes a latch member (150) engageable with a portion of the cartridge. A plunger rod (44) includes a protrusion (50) and is adapted to communicate with the latch member, the plunger rod being transitionable from a disengaged position, in which the protrusion of the plunger rod is disengaged from the latch member and the latch member is locked to the cartridge, to an engaged position, in which the protrusion is engaged with the latch member and the latch member is unlocked from the cartridge and locked to the plunger rod.
摘要翻译: 公开了一种包括用于与包含第一物质的盒(18)顺序接合的适配器(14)和包含第二物质的小瓶(16)的系统。 适配器被配置为首先与小瓶接合并且随后与盒接合,使得盒经由适配器与小瓶流体连通。 该系统包括可与盒的一部分接合的闩锁构件(150)。 柱塞杆(44)包括突起(50)并且适于与闩锁构件连通,柱塞杆可从分离位置转换,其中柱塞杆的突起与闩锁构件脱离,并且闩锁构件 被锁定到卡盘到接合位置,其中突起与闩锁构件接合,并且闩锁构件从盒中解锁并锁定到柱塞杆。
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公开(公告)号:US20150020919A1
公开(公告)日:2015-01-22
申请号:US14377553
申请日:2013-03-05
发明人: Haiming Wu , Richard Cronenberg
CPC分类号: A61J1/2089 , A61J1/062 , A61J1/1406 , A61J1/1481 , A61J1/201 , A61J1/2013 , B65B3/003
摘要: An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial includes a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial. The adapter includes a needle assembly having a first tip and a second tip, with the needle assembly disposed within the housing and at least partially supported by a needle holder. The needle assembly is movable relative to the housing from an initial position in which the first and second tip are isolated from the cartridge and vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, establishing fluid communication therebetween. The needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing.
摘要翻译: 用于在盒和小瓶之间建立双向流体连接的适配器组件包括具有适于接合盒的敞开的第一端和适于接合小瓶的第二开口端的壳体。 适配器包括具有第一尖端和第二末端的针组件,其中针组件设置在壳体内并且至少部分地由针保持器支撑。 针组件可以从其中第一和第二尖端与药筒和小瓶隔离的初始位置相对于壳体移动到使用位置的终点,其中第一尖端与小瓶接合,并且第二末端接合 与墨盒之间建立流体连通。 针组件通过锁定结构保持在初始位置,锁定结构通过相对于壳体旋转地推进针保持器而释放。
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公开(公告)号:US12102805B2
公开(公告)日:2024-10-01
申请号:US17194123
申请日:2021-03-05
发明人: Richard E. Cronenberg , Michael Quinn , Haiming Wu
CPC分类号: A61M5/31548 , A61M5/31535 , A61M5/31541 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31585 , A61M5/31595 , A61M5/24 , A61M2005/2407 , A61M5/2466 , A61M2005/2488 , A61M2005/2492 , A61M5/31543 , A61M5/3157 , A61M5/31573 , A61M5/31575 , A61M5/3202 , A61M5/347 , A61M2205/581
摘要: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.
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