公开(公告)号：US20240400893A1

公开(公告)日：2024-12-05

申请号：US18696125

申请日：2022-09-30

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Massimiliano Tomasulo ,  Sergei Gulnik

IPC: C09K11/06 ,  C09B69/10 ,  G01N33/533

Abstract: The present invention provides water-soluble tetrahydropyrene based fluorescent polymers, water-soluble tetrahydropyrene based tandem fluorescent polymers, water-soluble fluorescent polymer complexes, and their use in methods for detecting an analyte in a sample.

公开(公告)号：US20240270971A1

公开(公告)日：2024-08-15

申请号：US18558489

申请日：2022-05-03

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Massimiliano Tomasulo ,  Sergei Gulnik ,  Boi Hoa San

IPC: C09B69/10 ,  G01N33/58

CPC classification number: C09B69/109 ,  G01N33/582 ,  G01N2458/00

Abstract: The present disclosure provides UV-absorbing polymer dyes and methods for detecting an analyte in a sample by using a binding partner conjugated to a UV-absorbing polymer dye. Compositions comprising UV-absorbing polymer dyes, UV-absorbing tandem dyes, or quenched UV polymer dyes are provided.

公开(公告)号：US12018117B2

公开(公告)日：2024-06-25

申请号：US18094270

申请日：2023-01-06

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Sergei Gulnik ,  Massimiliano Tomasulo

IPC: C08G61/10 ,  C09B69/10 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/58

CPC classification number: C08G61/10 ,  C09B69/105 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/582 ,  C08G2261/11 ,  C08G2261/1424 ,  C08G2261/1432 ,  C08G2261/145 ,  C08G2261/1644 ,  C08G2261/18 ,  C08G2261/228 ,  C08G2261/314 ,  C08G2261/78 ,  C08G2261/94

Abstract: Water-soluble photoactive polymers, included polymer tandem dyes, as described as well as methods for their preparation and use. The photoactive polymers can be prepared by direct modification of core polymers (e.g., violet excitable polymers) with dyes or other functional groups. Methods of detecting analytes using the polymers are also described.

公开(公告)号：US11584825B2

公开(公告)日：2023-02-21

申请号：US16711131

申请日：2019-12-11

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Sergei Gulnik ,  Massimiliano Tomasulo

IPC: C08G61/10 ,  C09B69/10 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/58

Abstract: Water-soluble photoactive polymers, included polymer tandem dyes, as described as well as methods for their preparation and use. The photoactive polymers can be prepared by direct modification of core polymers (e.g., violet excitable polymers) with dyes or other functional groups. Methods of detecting analytes using the polymers are also described.

公开(公告)号：US20240301131A1

公开(公告)日：2024-09-12

申请号：US18663716

申请日：2024-05-14

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Sergei Gulnik ,  Massimiliano Tomasulo

IPC: C08G61/10 ,  C09B69/10 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/58

CPC classification number: C08G61/10 ,  C09B69/105 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/582 ,  C08G2261/11 ,  C08G2261/1424 ,  C08G2261/1432 ,  C08G2261/145 ,  C08G2261/1644 ,  C08G2261/18 ,  C08G2261/228 ,  C08G2261/314 ,  C08G2261/78 ,  C08G2261/94

Abstract: Water-soluble photoactive polymers, included polymer tandem dyes, as described as well as methods for their preparation and use. The photoactive polymers can be prepared by direct modification of core polymers (e.g., violet excitable polymers) with dyes or other functional groups. Methods of detecting analytes using the polymers are also described.

公开(公告)号：US20230399565A1

公开(公告)日：2023-12-14

申请号：US18207983

申请日：2023-06-09

Applicant: Beckman Coulter, Inc.

Inventor： Massimiliano Tomasulo ,  Mukesh Mudgal ,  Arunkumar Easwaran ,  Sergei Gulnik

IPC: C09K11/06

CPC classification number: C09K11/06 ,  C09K2211/1011

Abstract: The present disclosure provides fused dihydrophenanthrene (DHP) monomers and fluorescent fused DHP polymers, water-soluble fluorescent polymers and copolymers, water-soluble fluorescent polymer complexes, and their use in methods for detecting an analyte in a sample.

公开(公告)号：US20230192943A1

公开(公告)日：2023-06-22

申请号：US18094270

申请日：2023-01-06

Applicant: Beckman Coulter, Inc.

Inventor： Arunkumar Easwaran ,  Sergei Gulnik ,  Massimiliano Tomasulo

IPC: C08G61/10 ,  C09B69/10 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/58

CPC classification number: C08G61/10 ,  C09B69/105 ,  G01N33/533 ,  G01N33/542 ,  G01N33/545 ,  G01N33/582 ,  C08G2261/11 ,  C08G2261/18 ,  C08G2261/78 ,  C08G2261/94 ,  C08G2261/145 ,  C08G2261/228 ,  C08G2261/314 ,  C08G2261/1424 ,  C08G2261/1432 ,  C08G2261/1644

Abstract: Water-soluble photoactive polymers, included polymer tandem dyes, as described as well as methods for their preparation and use. The photoactive polymers can be prepared by direct modification of core polymers (e.g., violet excitable polymers) with dyes or other functional groups. Methods of detecting analytes using the polymers are also described.