公开(公告)号：US20240199560A1

公开(公告)日：2024-06-20

申请号：US18551614

申请日：2022-03-22

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Julia Johanna HAHN ,  Daniel GALLENKAMP

IPC: C07D277/54 ,  B01J31/04 ,  B01J31/22

CPC classification number: C07D277/54 ,  B01J31/04 ,  B01J31/2217 ,  B01J2231/70 ,  B01J2531/46 ,  B01J2531/842

Abstract: The present invention relates to a catalytic process for preparing 2-(phenylimino)-1,3-thiazolidin-4-one sulfoxide derivatives of formula (I) in enantiomerically pure or enantiomerically enriched form,






in which Y1, Y2, R1, R2 and R3 are as defined in the description.

公开(公告)号：US20220315545A1

公开(公告)日：2022-10-06

申请号：US17625278

申请日：2020-07-08

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Julia Johanna HAHN

IPC: C07D277/54

Abstract: The present invention relates to a method for preparing 2-(phenylimino)-1,3-thiazolidin-4-ones of the general formula (I). in which Y1, Y2, R1, R2 and R3 are as defined in the description.

公开(公告)号：US20220298126A1

公开(公告)日：2022-09-22

申请号：US17634401

申请日：2020-08-13

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Julia Johanna HAHN ,  Sergii PAZENOK ,  Silvia CEREZO-GALVEZ ,  Bernd ALIG

IPC: C07D277/38 ,  C07C335/28

Abstract: The present invention relates to a novel method for preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones of the general formula (I) in which Y1, Y2, R1, R2 and R3 are as defined in the description.

公开(公告)号：US20210403406A1

公开(公告)日：2021-12-30

申请号：US17045939

申请日：2019-04-03

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Dirk BROHM ,  Wahed Ahmed MORADI

IPC: C07C51/08 ,  C07C253/14 ,  C07C17/16 ,  C07C29/141 ,  C07C45/42 ,  C07F3/02

Abstract: The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5) activation of the benzyl alcohol obtained, (6) cyanation of the activated benzyl alcohol and (7) hydrolysis of the nitrile obtained.

公开(公告)号：US20240294539A1

公开(公告)日：2024-09-05

申请号：US18626788

申请日：2024-04-04

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Peter BRUECHNER ,  Werner LINDNER ,  Julia Johanna HAHN ,  Wahed Ahmed MORADI ,  Reiner FISCHER ,  Michael DOCKNER

IPC: C07D491/113 ,  C07C229/48 ,  C07C233/52 ,  C07D209/54

CPC classification number: C07D491/113 ,  C07C229/48 ,  C07C233/52 ,  C07D209/54 ,  C07C2601/14 ,  C07C2601/16

Abstract: The present invention relates to a novel process for preparing substituted cyclohexane amino acid esters and spiroketal-substituted cyclic keto-enols, and to novel intermediates or starting compounds that are passed through or used in the process according to the invention.

公开(公告)号：US20220348538A1

公开(公告)日：2022-11-03

申请号：US17763034

申请日：2020-10-13

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER

IPC: C07C319/24

Abstract: The present invention relates to a process for preparing 1,1′-disulfanediylbis(4-fluoro-2-methyl-5-nitrobenzene) which serves as an intermediate for the preparation of insecticidally, acaricidally and nematicidally active phenyl sulfoxides.

公开(公告)号：US20220251053A1

公开(公告)日：2022-08-11

申请号：US17625273

申请日：2020-07-08

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Julia Johanna HAHN

IPC: C07D277/38

Abstract: The present invention relates to a method for preparing 2-(phenylimino)-1,3-thiazolidin-4-ones of the general formula (I). in which Y1, Y2, R1, R2 and R3 are as defined in the description.

公开(公告)号：US20210139450A1

公开(公告)日：2021-05-13

申请号：US17047994

申请日：2019-04-15

Applicant: Bayer Aktiengesellschaft

Inventor： Albert SCHNATTERER ,  Michael DOCKNER ,  Peter BRUECHNER ,  Thomas HIMMLER

IPC: C07D317/72 ,  C07D491/113

Abstract: The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.

公开(公告)号：US20220267291A1

公开(公告)日：2022-08-25

申请号：US17743534

申请日：2022-05-13

Applicant: Bayer Aktiengesellschaft

Inventor： Albert SCHNATTERER ,  Michael DOCKNER ,  Peter BRUECHNER ,  Thomas HIMMLER

IPC: C07D317/72 ,  C07D491/113

Abstract: The present invention relates to a novel process for the esterification of N-acylated amino acids which contain an acid-labile keto protective group under alkaline conditions without using a polar aprotic solvent, in which the N-acylated amino acid with acid-labile keto protective group prepared in situ is esterified using an alkyl halide or a mono- or dialkyl ester of sulfuric acid.

公开(公告)号：US20210032262A1

公开(公告)日：2021-02-04

申请号：US17046156

申请日：2019-04-03

Applicant: Bayer Aktiengesellschaft

Inventor： Thomas HIMMLER ,  Peter BRUECHNER ,  Werner LINDNER ,  Julia Johanna HAHN ,  Wahed Ahmed MORADI ,  Reiner FISCHER ,  Michael DOCKNER

IPC: C07D491/113 ,  C07C233/52 ,  C07D209/54 ,  C07C229/48

Abstract: The present invention relates to a novel process for preparing substituted cyclohexane amino acid esters and spiroketal-substituted cyclic keto-enols, and to novel intermediates or starting compounds that are passed through or used in the process according to the invention.