公开(公告)号：US20230040008A1

公开(公告)日：2023-02-09

申请号：US17786768

申请日：2020-12-16

Applicant: BRACCO IMAGING S.P.A.

Inventor： Erika REITANO ,  Alessandro MAIOCCHI ,  Luisa POGGI ,  Federico CRIVELLIN ,  Simon HUET ,  Mathieu CINIER ,  Olivier KITTEN

IPC: C07K14/00 ,  A61K49/00 ,  C07K1/13

Abstract: The present invention provides new polypeptide derivatives binding to Human Epidermal Growth Factor Receptor 2 (HER2) and their conjugates thereof, and to their use as a diagnostic agent, particularly for early detection, patient stratification and treatment monitoring of forms of cancer characterized by over-expression of HER2.

公开(公告)号：US20230203129A1

公开(公告)日：2023-06-29

申请号：US17786669

申请日：2020-12-16

Applicant: BRACCO IMAGING S.P.A.

Inventor： Erika REITANO ,  Alessandro MAIOCCHI ,  Luisa POGGI ,  Federico CRIVELLIN ,  Simon HUET ,  Mathieu CINIER ,  Olivier KITTEN

IPC: C07K14/71 ,  C07K1/13 ,  G01N33/533

CPC classification number: C07K14/71 ,  C07K1/13 ,  G01N33/533

Abstract: The present invention provides new polypeptide derivatives binding to Human Epidermal Growth Factor Receptor 2 (HER2) and their conjugates thereof, and to their use as a diagnostic agent, particularly for early detection, patient stratification and treatment monitoring of forms of cancer characterized by over-expression of HER2.