公开(公告)号：US20240327345A1

公开(公告)日：2024-10-03

申请号：US18291284

申请日：2022-08-10

申请人： BILIX CO., LTD.

发明人： MYUNG LIP KIM ,  SANG HO MA ,  KI SOO PARK ,  HEE GOO JUN ,  DA EUN KIM

IPC分类号： C07D207/44

CPC分类号： C07D207/44

摘要： In a method of synthesizing bilirubin, a compound represented by Formula 2 is prepared by dimerizing a compound represented by Formula 1 or by coupling a compound represented by Formula 3 and a compound represented by Formula 4, thereby firstly chemically synthesizing bilirubin and PEGylated bilirubin, which are usefully used in a medical product or the like.

公开(公告)号：US20240239745A1

公开(公告)日：2024-07-18

申请号：US18291336

申请日：2022-08-10

申请人： BILIX CO., LTD.

发明人： MYUNG LIP KIM ,  SANG HO MA ,  KI SOO PARK ,  HEE GOO JUN ,  DA EUN KIM

IPC分类号： C07D207/337 ,  A61K47/60 ,  C07D207/333 ,  C07D207/38

CPC分类号： C07D207/337 ,  A61K47/60 ,  C07D207/333 ,  C07D207/38

摘要： In a method of synthesizing bilirubin according to an embodiment, a compound represented by Formula 3 is prepared by coupling a compound represented by Formula 1 with a compound represented by Formula 2, thereby firstly chemically synthesizing bilirubin and PEGylated bilirubin, which are usefully used in a medical product or the like.