知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

11 records (took 0.016 seconds)

    SYSTEMS AND METHODS FOR NORMALIZING SIGNALS IN BLOOD CULTURE MEASUREMENT SYSTEMS
    6.
    发明申请
    SYSTEMS AND METHODS FOR NORMALIZING SIGNALS IN BLOOD CULTURE MEASUREMENT SYSTEMS 有权

    公开(公告)号：US20210262936A1

    公开(公告)日：2021-08-26

    申请号：US17254794

    申请日：2019-06-24

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： James R. Petisce ,  Robert E. Armstrong ,  David J. Turner

    IPC: G01N21/64 ,  G01N33/49 ,  G01N21/80

    Abstract: Systems and methods for optimizing detection of optical signals indicating the presence of an analyte of interest in a blood sample are described. In one aspect, a blood culture test vial having a sensor is inoculated with the blood sample, light at an excitation frequency of the sensor is transmitted to the test vial, an intensity of a plurality of fluorescence signals emitted from the test vial is measured, and the plurality of measured fluorescence signals are normalized using by a reference signal that is not dependent on a measured intensity of a fluorescence signal emitted from the test vial. In another aspect, a measurement system measures fluorescence signals from one or more reference vials performing in extreme pH conditions. Fluorescence signals emitted from test vials inoculated with samples under test are measured and compared to the signals measured from the one or more reference vials to address or mitigate variability in hardware components of the measurement system.

    Glucose management and dialysis method and apparatus
    7.
    发明授权
    Glucose management and dialysis method and apparatus 有权
    葡萄糖管理和透析方法及仪器

    公开(公告)号：US08834401B2

    公开(公告)日：2014-09-16

    申请号：US13685320

    申请日：2012-11-26

    Applicant: Becton, Dickinson and Company

    Inventor： James R. Petisce ,  Andrew Metters

    IPC: A61M37/00 ,  A61M1/14 ,  A61M1/36

    CPC classification number: A61M1/14 ,  A61M1/342 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/3679 ,  A61M2202/0486 ,  A61M2230/201

    Abstract: A process and apparatus are provided for managing and adjusting glucose levels in the blood of a patient during dialysis. The apparatus is a dialysis apparatus to treat patients with renal disease which includes a glucose scavenger to remove excess glucose from the blood before returning the blood to the patient and/or a device to increase blood glucose levels in the blood when the glucose level is below a threshold level. The glucose scavenger can include a glucose binding protein, boronic acid derivative, boronic ester derivative or mixture thereof bonded to the surface of a support such as a fiber bundle in a cartridge or the inner surface of tubing used in the apparatus.

    Abstract translation: 提供了一种用于在透析期间管理和调节患者血液中的葡萄糖水平的方法和装置。 该装置是一种透析装置，用于治疗患有肾脏疾病的患者，其包括葡萄糖清除剂，以在血液返回到患者之前除去血液中的多余葡萄糖，和/或当葡萄糖水平低于血液时增加血液中血糖水平的装置 阈值水平。 葡萄糖清除剂可以包括葡萄糖结合蛋白，硼酸衍生物，硼酸酯衍生物或其混合物，其结合到载体的表面，例如药筒中的纤维束或装置中使用的管道的内表面。

    SYSTEMS AND METHODS OF BACTERIAL GROWTH DETECTION USING DUAL LIGHT EXCITATION
    8.
    发明申请
    SYSTEMS AND METHODS OF BACTERIAL GROWTH DETECTION USING DUAL LIGHT EXCITATION 有权

    公开(公告)号：US20240393246A1

    公开(公告)日：2024-11-28

    申请号：US18796851

    申请日：2024-08-07

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： James R. Petisce ,  Robert E. Armstrong ,  David J. Turner

    IPC: G01N21/64 ,  C12Q1/04 ,  G01N21/80

    Abstract: A method of determining the presence of an analyte of interest in a blood sample within a test device including a sensor in aqueous media includes transmitting light to the test device at a first excitation wavelength at which light absorption of the sensor remains substantially constant as pH of the aqueous media changes, measuring an intensity of a first fluorescence signal emitted from the sensor in the test device in response to the first excitation wavelength, transmitting light to the test device at a second excitation wavelength, the second excitation wavelength being different from the first excitation wavelength, measuring an intensity of a second fluorescence signal emitted from the sensor in the test device in response to the second excitation wavelength, and normalizing, with the first fluorescence signal, the intensity of the second fluorescence signal emitted from the test device in response to the second excitation wavelength.

    Insulin leakage sensor with electric control to stop insulin flow
    9.
    发明授权
    Insulin leakage sensor with electric control to stop insulin flow 有权

    公开(公告)号：US11311667B2

    公开(公告)日：2022-04-26

    申请号：US16500619

    申请日：2018-04-19

    Applicant: Becton, Dickinson and Company

    Inventor： James R. Petisce ,  Eric Bene

    IPC: A61M5/168 ,  A61M5/142

    Abstract: An insulin delivery device (10) includes a cannula (40) for delivering insulin to a patient at an infusion site, a pump assembly (30), and a valve (36) for controlling the flow of insulin. A removable leak detector unit (28) is coupled to the delivery device for sensing and detecting leakage of insulin at the infusion site. The leak detector unit (28) has electrodes (56) positioned for contacting the insulin leaking from the infusion site, a sensing electrical circuit (54) and a power source (58) for operating the leak detector unit. The removable leak detector unit (28) has an electrical contact (62) for mating with an electrical contact (64) of the delivery device for electrically and operatively connecting the leak detector unit (28) to the delivery device. The leak detector unit (28) sends a signal to the pump assembly (30) and/or valve (36) to stop the flow of insulin when leakage is detected at the infusion site.

Patent Agency Ranking