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公开(公告)号：US20240144629A1
公开(公告)日：2024-05-02
申请号：US18280997
申请日：2022-03-09
申请人： BD KIESTRA B.V.
发明人： Franciscus Hermannus Feijen , Brent Ronald Pohl , Craig W. Bark , Jan Bart Van Der Vijver , Timothy Roy Hansen , Jurjen Sinnema , Martijn Kleefstra
CPC分类号： G06V10/14 , G06V10/22 , G06V10/25 , G06V2201/034
摘要： A system that may automatically and rapidly process blood culture bottles. Such processing includes obtaining an image of a label placed on the cylindrical surface of the blood culture bottle. The system may also determine an amount of blood sample that has been added to the blood culture bottle by comparing a sample level to pre-placed fiducial. The distance between the liquid meniscus in the blood culture bottle and fiducial may be used to determine blood volume. The imaging apparatus may also detect internal conditions of the blood culture bottle such as the presence of foam or the presence of culture media in a neck portion of the blood culture bottle. The image of the label is obtained from one or more images captured by a camera or scanner. The information on the label may be read automatically and therefore the blood culture bottles do not have to be processed manually, increasing throughput of the apparatus.
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公开(公告)号：US20220290089A1
公开(公告)日：2022-09-15
申请号：US17632597
申请日：2020-08-05
申请人： BD KIESTRA B.V.
摘要： A multi-port disposable device that can both vent a sealed culture vessel and draw a sample therefrom into a collection vessel. The multi-port disposable device has a first port configured to receive the top portion of a culture vessel and attach thereto. The multi-port disposable device has a second port configured to receive a sample collection vessel. The multi-port disposable device has first and second needles. The first needle has a cannula configured to penetrate a septum or cap of the culture vessel. Optionally, the cannula terminates in a layer of foam that carries a microbial agent such that any vapor that is transmitted from the culture vessel through the cannula when venting the sealed culture vessel is absorbed by the foam. Optionally, the ports of the disposable device are configured as sleeves. The sleeve of the first port receives a portion of the culture vessel and the sleeve of the second port receives the collection vessel. The second needle has a cannula that penetrates both the septum or cap of the culture vessel and the septum or cap of the collection vessel, when the culture vessel and the collection vessel are brought into the device, thereby providing for fluid communication between the culture vessel and the collection vessel. The second cannula provides the flow pathway for delivering sample from the culture vessel to the collection vessel.
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公开(公告)号：US10921336B2
公开(公告)日：2021-02-16
申请号：US15575665
申请日：2016-05-27
申请人： BD Kiestra B.V.
发明人： Timothy Roy Hansen , Rick Holtz , Martijn Kleefstra , Raphael R. Marcelpoil , Rick Pierpont , Brent Ronald Pohl , Alyssa Shedlosky , Scott Shindledecker , Edward Skevington , Kerry Lynn Smith , Timothy M. Wiles
摘要： A method and automated apparatus for locating and selecting a colony of microorganisms on a culture dish and subjecting the obtained sample to a plurality of downstream tests including a test to identify the microorganism and a test to identify the susceptibility of the microorganism to antibiotics. The method includes the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of the selected colony of microorganisms; preparing a suspension of a sample of microorganisms automatically by submerging the pick tool with the sample in a suspension, after which the pick tool is vibrated in at least the vertical direction to release the sample from the pick tool in the suspension. The turbidity of the suspension is monitored to ensure that the concentration of microorganism in suspension is sufficient so that the suspension is used a source for sample for both identification and antibiotic susceptibility of the microorganisms in the sample. The apparatus and system optionally provides for downstream processing of samples prepared for antibiotic susceptibility testing (AST). Such apparatus includes further processing after inoculation of an AST panel for the AST test. Such further processing includes capping and transferring inoculated panels to AST instrument.
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公开(公告)号：US20210116471A1
公开(公告)日：2021-04-22
申请号：US17136670
申请日：2020-12-29
申请人： BD KIESTRA B.V.
发明人： Timothy R. Hansen , Rick Holtz , Martijn Kleefstra , Raphael Rodolphe Marcelpoil , Rick Pierpont , Brent Ronald Pohl , Alyssa Shedlosky , Scott Shindledecker , Edward Skevington , Kerry Lynn Smith , Timothy Wiles
摘要： A method and automated apparatus for locating and selecting a colony of microorganisms on a culture dish and subjecting the obtained sample to a plurality of downstream tests including a test to identify the microorganism and a test to identify the susceptibility of the microorganism to antibiotics. The method includes the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of the selected colony of microorganisms; preparing a suspension of a sample of microorganisms automatically by submerging the pick tool with the sample in a suspension, after which the pick tool is vibrated in at least the vertical direction to release the sample from the pick tool in the suspension. The turbidity of the suspension is monitored to ensure that the concentration of microorganism in suspension is sufficient so that the suspension is used a source for sample for both identification and antibiotic susceptibility of the microorganisms in the sample. The apparatus and system optionally provide for downstream processing of samples prepared for antibiotic susceptibility testing (AST). Such apparatus includes further processing after inoculation of an AST panel for the AST test. Such further processing includes capping and transferring inoculated panels to AST instrument.
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