公开(公告)号：US20240238390A1

公开(公告)日：2024-07-18

申请号：US17781947

申请日：2020-11-30

申请人： BCN PEPTIDES, S.A.

发明人： Jimena FERNÁNDEZ CARNEADO ,  Berta PONSATI ,  Antonio PARENTE DUEÑA ,  Mariona VALLÈS-MIRET ,  Josep FARRERA-SINFREU ,  Anna ALMAZÁN-MOGA ,  Josep ROMA-CASTANYER ,  Soledad GALLEGO MELCÓN ,  José SÁNCHEZ DE TOLEDO CODINA ,  Lucas MORENO MARTÍN-RETORTILLO ,  Natalia NAVARRO BAREA ,  Carla MOLIST MUÑOZ

IPC分类号： A61K38/48 ,  A61P35/00 ,  C12N9/64

CPC分类号： A61K38/4886 ,  A61P35/00 ,  C12N9/6489 ,  C12Y304/24

摘要： The present invention belongs to the field of biomedical chemistry and provides modified peptides and dimers thereof derived from the amino acid sequence of the protein ADAM-12, their compositions, process of synthesis and their use in medicine, specifically in the inhibition of cancer growth and/or the reduction or inhibition of cancer cell invasion and metastasis in different cancers.