公开(公告)号：US3615224A

公开(公告)日：1971-10-26

申请号：US3615224D

申请日：1969-11-13

Applicant: BAXTER LABORATORIES INC

Inventor： STERN IVAN J ,  FAREED JAWED

IPC: G01N33/52 ,  G01N21/00 ,  G01N31/04 ,  G01N33/16

CPC classification number: G01N33/52 ,  Y10T436/147777

Abstract: A method for the microdetermination of 2,8-dioxyadenine in whole blood plasma by strong acid cation exchange resin chromatography with a linear or stepwise gradient increase in concentration of HC1 for elution.

公开(公告)号：US3558433A

公开(公告)日：1971-01-26

申请号：US3558433D

申请日：1967-11-07

Applicant: BAXTER LABORATORIES INC

Inventor： STERN IVAN J

IPC: A61K38/46 ,  C12N9/50 ,  C07G7/022

CPC classification number: C12N9/50 ,  A61K38/4873 ,  B01D15/166 ,  B01D15/34 ,  C12Y304/22006 ,  Y10S435/815

Abstract: PROCESS FOR PURIFYING CHYMOPAPAIN BY CHROMATOGRAPHY OF AN AQUEOUS EXTRACT OF CRUDE CHYMOPAPAIN OR PAPAYA LATEX WITH CARBOXYMETHYL SUBSTGITUTED CROSS-LINKED DEXTRAN COPOLYMER EQUILIBRATED WITH AQUEOUS BUFFER SOLUTION FOLLOWED BY ELUTING WITH AQUEOUS BUFFER SOLUTION HAVING ABOUT THE SAME PH AS, BUT GREATER IONIC STRENGTH THAN THE BUFFER USED FOR EQUILIBRATING THE CHROMATOGRAPHIC COLUMN.