公开(公告)号：US3631018A

公开(公告)日：1971-12-28

申请号：US3631018D

申请日：1970-05-01

Applicant: BAXTER LABORATORIES INC

Inventor： SHANBROM EDWARD ,  FEKETE LAJOS F

IPC: A23J1/06 ,  A61K38/00 ,  C07K14/755 ,  C07G7/00

CPC classification number: A23J1/06 ,  A61K38/00 ,  C07K14/755 ,  Y10S530/83

Abstract: THE PRODUCTION OF A STABLE ANTIHEMOPHILIC FACTOR OF HIGH POTENCY BY THE FRACTIONATION OF A CRYOPRECIPITATE CONCENTRATE OF ANTIHEMOPHILIC FACTOR.

公开(公告)号：US3682881A

公开(公告)日：1972-08-08

申请号：US3682881D

申请日：1970-10-02

Applicant: BAXTER LABORATORIES INC

Inventor： FEKETE LAJOS F ,  SHANBROM EDWARD

IPC: A61K38/00 ,  C07K14/755 ,  C12N9/74 ,  C07G7/00

CPC classification number: C12N9/6429 ,  A61K38/00 ,  C07K14/755 ,  C12Y304/21005 ,  Y10S530/83

Abstract: CONCENTRATES OF ANTIHEMIPHILIC FACTOR A AND PROTHROMBIN COMPLEX ARE PREPARED FROM CITRATED BLOOD PLASMA BY AN INITIAL FRACTIONATION WITH GLYCINE FOLLOWED BY MULTIPLE FRACTIONATIONS OF THE AHF-CONTAINING PRECIPITATE AND THE PROTROMBIN COMPLEX-CONTAINING SUPERNATE WITH POLYETHYLENE GLYCOL, THE AHF-CONTAINING FRACTION BEING GIVEN AN ADDITIONAL FRACTIONATION WITH GLYCINE AND THE PROTHROMBIN COMPLEX-CONTAINING FRACTION BEING GIVEN AN INTERMEDIATE ADSORPTION WITH TRIBASIC CALCIUM PHOSPHATE.

公开(公告)号：US3560475A

公开(公告)日：1971-02-02

申请号：US3560475D

申请日：1969-06-19

Applicant: BAXTER LABORATORIES INC

Inventor： FEKETE LAJOS F ,  SHANBROM EDWARD

IPC: A61K38/00 ,  C12N9/74 ,  C07G7/00

CPC classification number: C12N9/6429 ,  A61K38/00 ,  C12Y304/21005 ,  Y10S530/831

Abstract: A PROTHROMBIN COMPLEX PREPARED FROM A PLASMA FRACTION CONTAINING FACTORS II, VII, IX AND X BY ADSORPTION WITH TRIBASIC CALCIUM PHOSPHATE, ELUTION WITH TRISODIUM CITRATE, AND MULTIPLE PRECIPITATIONS WITH POLYETHYLENE GLYCOL.

公开(公告)号：US3554702A

公开(公告)日：1971-01-12

申请号：US3554702D

申请日：1968-05-17

Applicant: BAXTER LABORATORIES INC

Inventor： SHANBROM EDWARD ,  KAMIENSKI EDWARD P JR

IPC: G01N33/487 ,  G01N31/02 ,  G01N33/16

CPC classification number: G01N33/487 ,  Y10S436/805

Abstract: A HOLDER IS MOVABLE IN A FIRST POSITION AT A PREDETERMINED RATE FOR INDIRECTLY DISPLAYING PARTICLES PRODUCED IN A TIME CONTROLLED REACTION IN A HOLDER SUPPORTED RECEPTACLE AND UNDER LIGHT PASSING THROUGH A PATH DEFINED BY THE HOLDER. THE HOLDER IS HELD IN A SECOND POSITION DURING A REACTION

PERIOD AND THERAFTER SPONTANEOUSLY ASSUMES THE FIRST POSITION.

公开(公告)号：US3497437A

公开(公告)日：1970-02-24

申请号：US3497437D

申请日：1967-06-21

Applicant: BAXTER LABORATORIES INC

Inventor： LOUDERBACK ALLAN L ,  NATLAND MARTIN C ,  SHANBROM EDWARD

IPC: G01N27/447 ,  B01K5/00

CPC classification number: G01N27/44747